2. Gene
  3. Vtcn1 - V-set domain containing T cell activation inhibitor 1 Gene

Vtcn1 - V-set domain containing T cell activation inhibitor 1 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: B7x; B7h4; B7s1

基因 ID: 242122 | 基因类型: protein coding

关于 Vtcn1

功能概要

Enables signaling receptor binding activity. Acts upstream of or within positive regulation of interleukin-2 production; regulation of T cell activation; and response to protozoan. Located in external side of plasma membrane. Is expressed in hemolymphoid system gland; lung; male reproductive gland or organ; and pancreas. Orthologous to human VTCN1 (V-set domain containing T cell activation inhibitor 1). [provided by Alliance of Genome Resources, Apr 2022]

Vtcn1 基因产物(3)

mRNA Protein Name
NM_001409755.1 NP_001396684.1 V-set domain containing T-cell activation inhibitor 1 isoform 2
NM_001409758.1 NP_001396687.1 V-set domain containing T-cell activation inhibitor 1 isoform 2
NM_178594.4 NP_848709.2 V-set domain containing T-cell activation inhibitor 1 isoform 1 precursor
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables signaling receptor binding IDA
IDA: 通过直接分析推断
16751379 MGI
enables signaling receptor binding IGI
IGI: 通过遗传相互作用推断
15585831 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within interleukin-4 production IMP
IMP: 通过突变表型推断
16914726 MGI
acts upstream of or within negative regulation of T cell activation IDA
IDA: 通过直接分析推断
15585831 MGI
acts upstream of or within positive regulation of T cell proliferation IMP
IMP: 通过突变表型推断
16751379 MGI
acts upstream of or within positive regulation of interleukin-2 production IMP
IMP: 通过突变表型推断
16751379 MGI
acts upstream of or within response to protozoan IMP
IMP: 通过突变表型推断
16914726 MGI
acts upstream of or within type II interferon production IMP
IMP: 通过突变表型推断
16914726 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in external side of plasma membrane IDA
IDA: 通过直接分析推断
17051145 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

V-set domain containing T-cell activation inhibitor 1

B7 homolog 4

immune costimulatory protein B7-H4

t cell costimulatory molecule B7x

重组 Vtcn1 蛋白

目录号 产品名 蛋白编号 纯度
HY-P7641 B7-H4 Protein, Mouse (HEK293, Fc) Q7TSP5/AAH32925.1 (F29-P258) ≥95%
HY-P74393 B7-H4 Protein, Mouse (sf9, His) Q7TSP5 (F29-S256) ≥95%
HY-P74394 B7-H4 Protein, Mouse (HEK293, His) Q7TSP5 (F29-S256) ≥95%

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS15721 VTCN1 Human Pre-designed siRNA Set A Pre-designed Sets / 否
抗体抑制剂 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-P990918 Emiltatug / 否
HY-P990953 Zubotamig Inhibitor / 否
HY-P990996 Felmetatug / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Vtcn1 NCBI NCBI:79679
Rattus norvegicus Vtcn1 NCBI NCBI:295322
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