2. Gene
  3. Slc9a1 - solute carrier family 9 member A1 Gene

Slc9a1 - solute carrier family 9 member A1 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Rattus norvegicus

同用名: Nhe1

基因 ID: 24782 | 基因类型: protein coding

关于 Slc9a1

功能概要

Enables sodium:proton antiporter activity. Involved in several processes, including cellular response to electrical stimulus; positive regulation of mitochondrial membrane permeability; and regulation of apoptotic process. Located in several cellular components, including T-tubule; basolateral plasma membrane; and intercalated disc. Used to study cataract; middle cerebral artery infarction; and proteinuria. Biomarker of hyperthyroidism; hypothyroidism; renovascular hypertension; and type 2 diabetes mellitus. Human ortholog(s) of this gene implicated in autosomal recessive spinocerebellar ataxia 19 and congestive heart failure. Orthologous to human SLC9A1 (solute carrier family 9 member A1). [provided by Alliance of Genome Resources, Apr 2022]

Slc9a1 基因产物(1)

mRNA Protein Name
NM_012652.2 NP_036784.1 sodium/hydrogen exchanger 1
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
12576672 RGD
enables sodium:proton antiporter activity IDA
IDA: 通过直接分析推断
18321853 RGD
enables sodium:proton antiporter activity IMP
IMP: 通过突变表型推断
16002403 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in cardiac muscle cell contraction IEP
IEP: 通过表达模式推断
20868366 RGD
involved in cell differentiation IEP
IEP: 通过表达模式推断
16495213 RGD
involved in cellular response to antibiotic IEP
IEP: 通过表达模式推断
20868366 RGD
involved in cellular response to cold IEP
IEP: 通过表达模式推断
15452191 RGD
involved in cellular response to electrical stimulus IEP
IEP: 通过表达模式推断
20868366 RGD
involved in cellular response to hypoxia IDA
IDA: 通过直接分析推断
20868366 RGD
involved in cellular response to insulin stimulus IDA
IDA: 通过直接分析推断
20868366 RGD
involved in cellular response to organic cyclic compound IEP
IEP: 通过表达模式推断
20868366 RGD
involved in negative regulation of apoptotic process IMP
IMP: 通过突变表型推断
17552965 RGD
involved in positive regulation of action potential IMP
IMP: 通过突变表型推断
18319243 RGD
involved in positive regulation of apoptotic process IMP
IMP: 通过突变表型推断
22407349 RGD
involved in positive regulation of cell growth IMP
IMP: 通过突变表型推断
19687166 RGD
involved in positive regulation of intracellular signal transduction IMP
IMP: 通过突变表型推断
14600156 RGD
involved in positive regulation of mitochondrial membrane permeability IMP
IMP: 通过突变表型推断
21297023 RGD
involved in regulation of intracellular pH IMP
IMP: 通过突变表型推断
22387884 RGD
involved in regulation of the force of heart contraction IMP
IMP: 通过突变表型推断
21659487 RGD
involved in response to acidic pH IDA
IDA: 通过直接分析推断
18321853 RGD
involved in response to organic cyclic compound IDA
IDA: 通过直接分析推断
17308111 RGD
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in T-tubule IDA
IDA: 通过直接分析推断
20868366 RGD
located in apical plasma membrane IDA
IDA: 通过直接分析推断
23869188 RGD
located in basolateral plasma membrane IDA
IDA: 通过直接分析推断
9438178 RGD
located in cell surface IDA
IDA: 通过直接分析推断
20868366 RGD
located in intercalated disc IDA
IDA: 通过直接分析推断
20868366 RGD
located in perinuclear region of cytoplasm IDA
IDA: 通过直接分析推断
20868366 RGD
located in plasma membrane IDA
IDA: 通过直接分析推断
18321853 RGD
located in sarcolemma IDA
IDA: 通过直接分析推断
20868366 RGD
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

sodium/hydrogen exchanger 1

NHE-1

Na(+)/H(+) exchanger 1

Solute carrier family 9 (sodium/hydrogen exchanger 1), antiporter, Na+/H+, (amiloride sensitive)

solute carrier family 9 (sodium/hydrogen exchanger), member 1

solute carrier family 9 member 1

solute carrier family 9, subf

Slc9a1 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
Intra Slc9a1 P26431 Chp2 Rattus norvegicus Q810D1
Pull Down
12576672
种属间: 跨种属相互作用 种属内: 同种属相互作用

相关产品

Pre-clinical Phase
生物活性分子 (2)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS13341 SLC9A1 Human Pre-designed siRNA Set A Pre-designed Sets / 否
HY-RS13349 SLC9B1 Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Slc9a1 NCBI NCBI:6548
嗨！很高兴为您提供帮助！

尊敬的 MCE 客户您好，
请您选择所在区域，我们将转接对应客服为您服务！

热门区域

A

B

C

F

G

H

J

L

N

Q

S

T

X

Y

Z

热 A B C F G H J L N Q S T X Y Z