2. Gene
  3. Pdgfa - platelet derived growth factor subunit A Gene

Pdgfa - platelet derived growth factor subunit A Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Rattus norvegicus

同用名: PDGFACP

基因 ID: 25266 | 基因类型: protein coding

关于 Pdgfa

功能概要

Predicted to enable several functions, including platelet-derived growth factor binding activity; protein dimerization activity; and signaling receptor binding activity. Involved in several processes, including male gonad development; response to estradiol; and response to retinoic acid. Predicted to be located in cell surface and microvillus. Predicted to be active in extracellular space. Biomarker of chronic ulcer of skin; oligohydramnios; pancreatitis; pulmonary hypertension; and renovascular hypertension. Human ortholog(s) of this gene implicated in high grade glioma. Orthologous to human PDGFA (platelet derived growth factor subunit A). [provided by Alliance of Genome Resources, Apr 2022]

Pdgfa 基因产物(1)

mRNA Protein Name
NM_012801.2 NP_036933.2 platelet-derived growth factor subunit A precursor
基因本体论
  • 生物过程
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in cellular response to transforming growth factor beta stimulus IEP
IEP: 通过表达模式推断
16039137 RGD
involved in inner ear development IEP
IEP: 通过表达模式推断
15267171 RGD
involved in male gonad development IEP
IEP: 通过表达模式推断
11870082 RGD
involved in positive regulation of cell population proliferation IMP
IMP: 通过突变表型推断
15267171 RGD
involved in response to estradiol IEP
IEP: 通过表达模式推断
14724432 RGD
involved in response to hypoxia IEP
IEP: 通过表达模式推断
8447423 RGD
involved in response to retinoic acid IEP
IEP: 通过表达模式推断
15315332 RGD
involved in response to xenobiotic stimulus IEP
IEP: 通过表达模式推断
16414398 RGD
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

platelet-derived growth factor subunit A

PDGF subunit A

PDGF-1

Platelet-derived growth factor A chain

platelet derived growth factor, alpha

platelet-derived growth factor alpha polypeptide

重组 Pdgfa 蛋白

目录号 产品名 蛋白编号 纯度
HY-P73720 PDGF-AA Protein, Rat (P.pastoris, His) P28576-2/NP_036933.2 (S87-R196) ≥95%

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS10250 PDGFA Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Pdgfa NCBI NCBI:5154
Canis familiaris Pdgfa NCBI NCBI:491597
Mus musculus Pdgfa NCBI NCBI:18590
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