2. Gene
  3. Il15 - interleukin 15 Gene

Il15 - interleukin 15 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

中文名称：白细胞介素 15

种属: Rattus norvegicus

基因 ID: 25670 | 基因类型: protein coding

关于 Il15

Primary_assembly 19: 25,640,251-25,706,820 forward strand.mRatBN7.2:CM026992.1

This gene has 2 transcripts (splice variants), 128 orthologues and is associated with 46 phenotypes. Biased expression in Lung (RPKM 129.7), Muscle (RPKM 78.1) and 9 other tissues.

功能概要

预测该基因编码的蛋白可启动细胞因子活性。参与多个过程，包括细胞对维生素 D 的反应； STAT 蛋白酪氨酸磷酸化的正向调控；和骨骼肌萎缩。位于细胞表面和细胞外空间。用于研究胰腺炎。李斯特菌病和牙周病的生物标志物。该基因的人类直系同源物与曲霉病有关；哮喘;胸膜炎;和 1 型糖尿病。与人 IL15（白细胞介素 15）同源。 [由基因组资源联盟提供，2022 年 4 月]

Predicted to enable cytokine activity. Involved in several processes, including cellular response to vitamin D; positive regulation of tyrosine phosphorylation of STAT protein; and skeletal muscle atrophy. Located in cell surface and extracellular space. Used to study pancreatitis. Biomarker of listeriosis and periodontal disease. Human ortholog(s) of this gene implicated in aspergillosis; asthma; pleurisy; and type 1 diabetes mellitus. Orthologous to human IL15 (interleukin 15). [provided by Alliance of Genome Resources, Apr 2022]

Il15 基因产物(2)

mRNA Protein Name
NM_001401135.1 NP_001388064.1 interleukin-15 preproprotein
NM_013129.3 NP_037261.1 interleukin-15 preproprotein
基因本体论
  • 生物过程
  • 细胞组分
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in cellular response to vitamin D IEP
IEP: 通过表达模式推断
15637289 RGD
involved in hyaluronan metabolic process IDA
IDA: 通过直接分析推断
17667861 RGD
involved in negative regulation of smooth muscle cell proliferation IMP
IMP: 通过突变表型推断
17667861 RGD
involved in positive regulation of cell population proliferation IMP
IMP: 通过突变表型推断
9826341 RGD
involved in positive regulation of protein modification process IDA
IDA: 通过直接分析推断
8942753 RGD
involved in response to nutrient levels IEP
IEP: 通过表达模式推断
19396981 RGD
involved in skeletal muscle atrophy IEP
IEP: 通过表达模式推断
17135303 RGD
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in cell surface IDA
IDA: 通过直接分析推断
16002563 RGD
located in extracellular space IDA
IDA: 通过直接分析推断
17667861 RGD
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

interleukin-15

IL-15

相关产品

Approval
抗体抑制剂 (1)
目录号 产品名 作用方式
纯度 是否罕见病
HY-P99661 Inbakicept Activator 98.95% 否
Clinical Phase
抗体抑制剂 (2)
目录号 产品名 作用方式
纯度 Phase
HY-P99850 Depemokimab Inhibitor 95.24% Phase 3
HY-P99410 Ordesekimab Inhibitor 95.00% Phase 2
Pre-clinical Phase
生物活性分子 (8)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-15898 Y-320 99.74% 否
HY-102049 IL-15-IN-1 Inhibitor 99.42% 否
HY-Y0493 HODHBt Inhibitor 99.93% 否
HY-153050 JAK-IN-24 Inhibitor 99.27% 否
HY-RS06690 IL15 Human Pre-designed siRNA Set A Pre-designed Sets / 否
HY-RS06691 Il15 Mouse Pre-designed siRNA Set A Pre-designed Sets / 否
HY-RS06692 Il15 Rat Pre-designed siRNA Set A Pre-designed Sets / 否
HY-RS06693 IL15RA Human Pre-designed siRNA Set A Pre-designed Sets / 否
抗体抑制剂 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-P990719 Efbalropendekin alfa / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Il15 NCBI NCBI:3600
Mus musculus Il15 NCBI NCBI:16168
Susscrofa domestica Il15 NCBI
Macaca mulatta Il15 NCBI NCBI:699616
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