BRI3 - brain protein I3 Gene

中文名称：脑蛋白 I3

种属: Homo sapiens

同用名: I3

基因 ID: 25798 | 基因类型: protein coding

关于 BRI3

Cytogenetic location: 7q21.3 Genomic coordinates (GRCh38): 7:98,281,686-98,323,430 (from NCBI)

This gene has 7 transcripts (splice variants) and 187 orthologues. Ubiquitous expression in lung (RPKM 12.8), stomach (RPKM 11.3) and 25 other tissues.

功能概要

实现相同的蛋白质结合活性。预测位于嗜天青颗粒膜和质膜上。 [由基因组资源联盟提供，2022 年 4 月]

Enables identical protein binding activity. Predicted to be located in azurophil granule membrane and plasma membrane. [provided by Alliance of Genome Resources, Apr 2022]

BRI3 基因产物(2)

mRNA	Protein	Name
NM_001159491.2	NP_001152963.1	brain protein I3 isoform b
NM_015379.5	NP_056194.1	brain protein I3 isoform a

基因本体论

分子功能

分子功能 GO 注释	逻辑证据	参考文献	来源
enables identical protein binding	IDA IDA: 通过直接分析推断	15606899	GOA
enables protein binding	IPI IPI: 通过物理相互作用推断	11860200	GOA

EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

BRI3 蛋白结构

DUF2367

0
100
125 a.a.

蛋白主名

其他名称

brain protein I3

pRGR2

BRI3 蛋白互作信息

分类	蛋白名称	蛋白编号	互作蛋白	互作蛋白种属	互作蛋白编号	实验方法	参考文献
Intra	BRI3	O95415	ABHD16A	Homo sapiens	O95870	Validated Y2H	32296183
Intra	BRI3	O95415	BRI3BP	Homo sapiens	Q8WY22	Anti Tag CoIP	30983867
Intra	BRI3	O95415	BRI3BP	Homo sapiens	Q8WY22	Y2H	11860200
Intra	BRI3	O95415	MGAT1	Homo sapiens	P26572	Confocal	30983867
Intra	BRI3	O95415	MGAT1	Homo sapiens	P26572	Anti Tag CoIP	30983867
Intra	BRI3	O95415	MGAT1	Homo sapiens	P26572	Y2H	30983867
Intra	BRI3	O95415	MALL	Homo sapiens	Q13021	Validated Y2H	32296183
Intra	BRI3	O95415	IFITM3	Homo sapiens	Q01628	Anti Tag CoIP	30983867
Intra	BRI3	O95415	IFITM3	Homo sapiens	Q01628	Confocal	30983867
Intra	BRI3	O95415	IFITM3	Homo sapiens	Q01628	Y2H	30983867

种属间: 跨种属相互作用 种属内: 同种属相互作用

关联疾病

疾病名称

别名

Developmental And Epileptic Encephalopathy 45

DEE45	Epileptic Encephalopathy, Early Infantile, 45
Eiee45	Developmental And Epileptic Encephalopathy, 45
Early Infantile Epileptic Encephalopathy 45

Developmental And Epileptic Encephalopathy 46

DEE46	Epileptic Encephalopathy, Early Infantile, 46
Eiee46	Developmental And Epileptic Encephalopathy, 46
Early Infantile Epileptic Encephalopathy 46

Developmental And Epileptic Encephalopathy 49

DEE49	Epileptic Encephalopathy, Early Infantile, 49
Eiee49	Developmental And Epileptic Encephalopathy, 49
Early Infantile Epileptic Encephalopathy 49

Developmental And Epileptic Encephalopathy 34

DEE34	Epileptic Encephalopathy, Early Infantile, 34
Eiee34	Developmental And Epileptic Encephalopathy, 34
Early Infantile Epileptic Encephalopathy 34

Developmental And Epileptic Encephalopathy 42

DEE42	Epileptic Encephalopathy, Early Infantile, 42
Eiee42	Developmental And Epileptic Encephalopathy, 42
Early Infantile Epileptic Encephalopathy 42	Encephalopathy, Epileptic, Early Infantile, Type 42

Developmental And Epileptic Encephalopathy 4

DEE4	Epileptic Encephalopathy, Early Infantile, 4
Eiee4	Early Infantile Epileptic Encephalopathy 4
Stxbp1-Related Early-Onset Encephalopathy	Early Myoclonic Encephalopathy
Developmental And Epileptic Encephalopathy, 4	Stxbp1 Disorders
Stxbp1 Encephalopathy	Developmental And Epileptic Encephalopathy, Type 4
Early-Infantile Epileptic Encephalopathy 4	Stxbp1 Encephalopathy With Epilepsy
Stxbp1 Epileptic Encephalopathy	Stxbp1-Related Developmental And Epileptic Encephalopathy
Stxbp1-Related Epileptic Encephalopathy	Eme
Neonatal Epilepsy With Suppression-Burst Pattern	Encephalopathy, Epileptic, Early Infantile, Type 4

Retinitis Pigmentosa 3

RP3	Retinitis Pigmentosa 15
Rp15	Choroidoretinal Degeneration With Retinal Reflex In Heterozygous Women
Cone-Rod Degeneration, X-Linked	Retinitis Pigmentosa Type 15
X-Linked Cone-Rod Degeneration	X-Linked Retinitis Pigmentosa 3
Xlrp3	Xlrp-3
Retinitis Pigmentosa-3	Retinitis Pigmentosa, Type 3

疾病名称	别名
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Cat. No.	产品名	作用方式	纯度	是否罕见病
HY-RS01618	BRI3 Human Pre-designed siRNA Set A	Pre-designed Sets	/	否
HY-RS01619	BRI3BP Human Pre-designed siRNA Set A	Pre-designed Sets	/	否

直系同源

种属	基因名	来源	基因 ID
Bos taurus	BRI3	VGNC	VGNC:26564
Canis familiaris	BRI3	VGNC	VGNC:38525
Mus musculus	BRI3	MGD	MGI:1933174
Rattus norvegicus	BRI3	RGD	RGD:1309187
Macaca mulatta	BRI3	VGNC	VGNC:70283
Felis catus	BRI3	VGNC	VGNC:107742

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MedChemExpress (MCE) 只为有资质的科研机构、医药企业基于科学研究或药证申报的用途提供医药研发服务，不为任何个人或者非科研性质的、非用于药证申报使用等其他用途提供服务。

站点地图隐私声明

沪ICP备15051369号-4

上海工商

沪公网安备31011502019417

沪(浦)应急管危经许[2021]201709(QFYS)

营业执照（三证合一）

BRI3 - brain protein I3 Gene

关于 BRI3

功能概要

BRI3 基因产物(2)

BRI3 蛋白结构

BRI3 蛋白互作信息

关联疾病

直系同源

热门区域

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BRI3 - brain protein I3 Gene

关于 BRI3

功能概要

BRI3 基因产物(2)

BRI3 蛋白结构

BRI3 蛋白互作信息

关联疾病

相关产品

直系同源

热门区域

A

B

C

F

G

H

J

L

N

Q

S

T

X

Y

Z