2. Gene
  3. ARMC8 - armadillo repeat containing 8 Gene

ARMC8 - armadillo repeat containing 8 Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：含犰狳重复 8

种属: Homo sapiens

同用名: GID5; VID28; S863-2; HSPC056

基因 ID: 25852 | 基因类型: protein coding

关于 ARMC8

Cytogenetic location: 3q22.3 Genomic coordinates (GRCh38): 3:138,187,248-138,298,389 (from NCBI)

This gene has 23 transcripts (splice variants) and 211 orthologues. Ubiquitous expression in bone marrow (RPKM 8.0), thyroid (RPKM 5.8) and 25 other tissues.

功能概要

预计参与蛋白酶体介导的泛素依赖性蛋白质分解代谢过程。位于细胞质和核质中。泛素连接酶复合物的一部分。 [由基因组资源联盟提供，2022 年 4 月]

Predicted to be involved in proteasome-mediated ubiquitin-dependent protein catabolic process. Located in cytosol and nucleoplasm. Part of ubiquitin Ligase complex. [provided by Alliance of Genome Resources, Apr 2022]

ARMC8 基因产物(8)

mRNA Protein Name
NM_001267041.2 NP_001253970.1 armadillo repeat-containing protein 8 isoform 3
NM_001267042.3 NP_001253971.1 armadillo repeat-containing protein 8 isoform 4
NM_001282342.2 NP_001269271.1 armadillo repeat-containing protein 8 isoform 5
NM_001363941.2 NP_001350870.1 armadillo repeat-containing protein 8 isoform 6
NM_001363942.1 NP_001350871.1 armadillo repeat-containing protein 8 isoform 7
NM_014154.4 NP_054873.2 armadillo repeat-containing protein 8 isoform 1
NM_015396.6 NP_056211.2 armadillo repeat-containing protein 8 isoform 2
NM_213654.3 NP_998819.1 armadillo repeat-containing protein 8 isoform 1
基因本体论
  • 分子功能
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
17467196 GOA
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in cytoplasm IDA
IDA: 通过直接分析推断
17467196 GOA
located in nucleus IDA
IDA: 通过直接分析推断
17467196 GOA
part of ubiquitin ligase complex IDA
IDA: 通过直接分析推断
29911972 GOA
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

ARMC8 蛋白结构

Arm

Arm: Armadillo/beta-catenin-like repeat (50 - 91)

  • 0
  • 200
  • 400
  • 600
  • 673 a.a.
蛋白主名 其他名称

armadillo repeat-containing protein 8

GID complex subunit 5, VID28 homolog

ARMC8 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
种属内
ARMC8 Q8IUR7 TCF12 Homo sapiens Q99081
Y2H Prey Pooling
25416956
种属间: 跨种属相互作用 种属内: 同种属相互作用

关联疾病

疾病名称 别名
Marinesco-Sjogren Syndrome

Marinesco-Sjögren Syndrome

MSS

Marinesco-Garland Syndrome

Garland-Moorhouse Syndrome

Hereditary Oligophrenic Cerebello-Lental Degeneration

Oligophrenic Cerebellolenticular Degeneration

Marinesco-Sjogren Syndrome-Hypergonadotrophic Hypogonadism

Marinesco-Sjogren Syndrome-Myopathy

Marinesco-Sjogren-Garland Syndrome

Marinesco-Sjoegren Syndrome
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS01005 ARMC8 Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Felis catus ARMC8 VGNC VGNC:59937
Bos taurus ARMC8 VGNC VGNC:26162
Canis familiaris ARMC8 VGNC VGNC:38128
Rattus norvegicus ARMC8 RGD RGD:1310477
Mus musculus ARMC8 MGD MGI:1921375
Macaca mulatta ARMC8 VGNC VGNC:69898
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