2. Gene
  3. MAGI3 - membrane associated guanylate kinase, WW and PDZ domain containing 3 Gene

MAGI3 - membrane associated guanylate kinase, WW and PDZ domain containing 3 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

中文名称：含膜相关鸟苷酸激酶，WW 和 PDZ 结构域 3

种属: Homo sapiens

同用名: MAGI-3; dJ730K3.2

基因 ID: 260425 | 基因类型: protein coding

关于 MAGI3

Cytogenetic location: 1p13.2 Genomic coordinates (GRCh38): 1:113,390,515-113,685,923 (from NCBI)

This gene has 6 transcripts (splice variants), 295 orthologues and 6 paralogues. Broad expression in lung (RPKM 6.5), thyroid (RPKM 5.4) and 24 other tissues.

功能概要

预测启用卷曲绑定活动。预计参与信号转导。预计在 JUN 激酶活性的正调节上游或正调节内起作用。位于细胞连接处。 [由基因组资源联盟提供，2022 年 4 月]

Predicted to enable Frizzled binding activity. Predicted to be involved in signal transduction. Predicted to act upstream of or within positive regulation of JUN kinase activity. Located in cell junction. [provided by Alliance of Genome Resources, Apr 2022]

MAGI3 基因产物(2)

mRNA Protein Name
NM_001142782.2 NP_001136254.1 membrane-associated guanylate kinase, WW and PDZ domain-containing protein 3 isoform 1
NM_152900.3 NP_690864.2 membrane-associated guanylate kinase, WW and PDZ domain-containing protein 3 isoform 2
基因本体论
  • 分子功能
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
16316992 GOA
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

MAGI3 蛋白结构

Guanylate_kin

Guanylate_kin: Guanylate kinase (129 - 192)

WW

WW: WW domain (295 - 324)

WW

WW: WW domain (341 - 370)

PDZ

PDZ: PDZ domain (Also known as DHR or GLGF) (413 - 477)

PDZ

PDZ: PDZ domain (Also known as DHR or GLGF) (730 - 806)

PDZ

PDZ: PDZ domain (Also known as DHR or GLGF) (852 - 934)

PDZ

PDZ: PDZ domain (Also known as DHR or GLGF) (1022 - 1099)

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  • 1481 a.a.
蛋白主名 其他名称

membrane-associated guanylate kinase, WW and PDZ domain-containing protein 3

membrane-associated guanylate kinase inverted 3

MAGI3 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
Intra MAGI3 Q5TCQ9 ADRB2 Homo sapiens P07550
Anti Tag CoIP
20353789
Intra MAGI3 Q5TCQ9 ADRB2 Homo sapiens P07550
Pull Down
20353789
Intra MAGI3 Q5TCQ9 MED28 Homo sapiens Q9H204
Peptide Array
16964398
Intra MAGI3 Q5TCQ9 ADRB1 Homo sapiens P08588
IF
16316992
Intra MAGI3 Q5TCQ9 ADRB1 Homo sapiens P08588
Peptide Array
16316992
种属间: 跨种属相互作用 种属内: 同种属相互作用

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS07983 MAGI3 Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Macaca mulatta MAGI3 VGNC VGNC:74400
Mus musculus MAGI3 MGD MGI:1923484
Bos taurus MAGI3 VGNC VGNC:31148
Felis catus MAGI3 VGNC VGNC:63366
Canis familiaris MAGI3 VGNC VGNC:42929
Rattus norvegicus MAGI3 RGD RGD:621362
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