2. Gene
  3. RAB11FIP5 - RAB11 family interacting protein 5 Gene

RAB11FIP5 - RAB11 family interacting protein 5 Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：RAB11 家族相互作用蛋白 5

种属: Homo sapiens

同用名: GAF1; pp75; RIP11; gaf-1; rab11-FIP5

基因 ID: 26056 | 基因类型: protein coding

关于 RAB11FIP5

Cytogenetic location: 2p13.2 Genomic coordinates (GRCh38): 2:73,073,382-73,112,948 (from NCBI)

This gene has 6 transcripts (splice variants), 285 orthologues and 2 paralogues. Broad expression in testis (RPKM 48.5), kidney (RPKM 16.7) and 18 other tissues.

功能概要

启用 γ-微管蛋白结合活性。参与细胞对酸性 pH 值的反应；脂联素分泌的负调节；和调节蛋白质在细胞表面的定位。位于中心粒卫星和线粒体外膜。 [由基因组资源联盟提供，2022 年 4 月]

Enables gamma-tubulin binding activity. Involved in cellular response to acidic pH; negative regulation of Adiponectin secretion; and regulation of protein localization to cell surface. Located in centriolar satellite and mitochondrial outer membrane. [provided by Alliance of Genome Resources, Apr 2022]

RAB11FIP5 基因产物(2)

mRNA Protein Name
NM_001371272.1 NP_001358201.1 rab11 family-interacting protein 5 isoform 1
NM_015470.3 NP_056285.1 rab11 family-interacting protein 5 isoform 2
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables gamma-tubulin binding IDA
IDA: 通过直接分析推断
11278501 GOA
enables protein binding IPI
IPI: 通过物理相互作用推断
11278501 GOA
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in cellular response to acidic pH IDA
IDA: 通过直接分析推断
20717956 GOA
involved in negative regulation of adiponectin secretion IDA
IDA: 通过直接分析推断
24040321 GOA
involved in regulation of protein localization to cell surface IMP
IMP: 通过突变表型推断
20717956 GOA
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in mitochondrial outer membrane IDA
IDA: 通过直接分析推断
11278501 GOA
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

RAB11FIP5 蛋白结构

C2

C2: C2 domain (22 - 84)

RBD-FIP

RBD-FIP: FIP domain (601 - 648)

  • 0
  • 100
  • 200
  • 300
  • 400
  • 500
  • 600
  • 653 a.a.
蛋白主名 其他名称

rab11 family-interacting protein 5

RAB11 family interacting protein 5 (class I)

关联疾病

疾病名称 别名
Neonatal Lupus Erythematosus

Neonatal Systemic Lupus Erythematosus
Mucocutaneous Leishmaniasis

American Cutaneous Leishmaniasis

American Mucocutaneous Leishmaniasis

Cutaneous Leishmaniasis, American

Mucocutaneous Leishmaniasis, American

New World Cutaneous Leishmaniasis

Leishmaniasis, Mucocutaneous

Espundia

Leishmania Braziliensis Infection
Splenic Disease

Splenic Diseases

Dyssplenism

Spleen Disease

Abnormality Of The Spleen

Spleen Diseases
Visceral Leishmaniasis

Kala-Azar

Leishmaniasis, Visceral

Infection By Visceral Leishmaniasis

Leishmaniasis Visceral

Sahib Disease

Ponos

Burdwan Fever

Mard El Bicha

Sirkari Disease

Indian Visceral Leishmaniasis

Dumdum Fever

Visceral Leishmaniasis Due To Leishmania Donovani
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS11520 RAB11FIP5 Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Felis catus RAB11FIP5 VGNC VGNC:64471
Bos taurus RAB11FIP5 VGNC VGNC:54474
Canis familiaris RAB11FIP5 VGNC VGNC:45252
Mus musculus RAB11FIP5 MGD MGI:1098586
Rattus norvegicus RAB11FIP5 RGD RGD:1592069
Macaca mulatta RAB11FIP5 VGNC VGNC:106203
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