1. Gene
  2. Avpr1b - arginine vasopressin receptor 1B Gene

Avpr1b - arginine vasopressin receptor 1B Gene

中文名称:精氨酸加压素受体 1B

种属: Mus musculus

同用名: VIBR; VPR3; AVPR3; V3/V1b

基因 ID: 26361 | 基因类型: protein coding

关于 Avpr1b

Chromosome 1: 131,526,977-131,539,738 forward strand.GRCm39:CM000994.3

This gene has 2 transcripts (splice variants), 132 orthologues, 16 paralogues and is associated with 7 phenotypes. Low expression observed in reference dataset.

功能概要

预测该基因编码的蛋白可启动肽结合活性和加压素受体活性。参与多细胞生物体的衰老和血压调节。通过加压素作用于全身动脉血压调节的上游或调节范围内。预测位于高尔基体和质膜。预计是质膜的组成部分。以多种结构表达,包括消化系统;脑;眼睛;泌尿生殖系统;和免疫系统。该基因的人类直系同源物与自闭症谱系障碍有关;躁郁症;和情绪障碍。与人类 AVPR1B(精氨酸加压素受体 1B)同源。 [由基因组资源联盟提供,2022 年 4 月]

Predicted to enable peptide binding activity and Vasopressin Receptor activity. Involved in multicellular organism aging and regulation of blood pressure. Acts upstream of or within regulation of systemic arterial blood pressure by vasopressin. Predicted to be located in Golgi apparatus and plasma membrane. Predicted to be integral component of plasma membrane. Is expressed in several structures, including alimentary system; brain; eye; genitourinary system; and immune system. Human ortholog(s) of this gene implicated in autism spectrum disorder; bipolar disorder; and mood disorder. Orthologous to human AVPR1B (arginine Vasopressin Receptor 1B). [provided by Alliance of Genome Resources, Apr 2022]

Avpr1b 基因产物(1)

mRNA Protein Name
NM_011924.2 NP_036054.1 vasopressin V1b receptor
基因本体论
  • 生物过程
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in regulation of blood pressure IMP
IMP: 通过突变表型推断
26531127 MGI
acts upstream of or within regulation of systemic arterial blood pressure by vasopressin IGI
IGI: 通过遗传相互作用推断
12486173 MGI
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断

Avpr1b 蛋白结构

7tmA_V1bR

7tmA_V1bR: cd15386 (34 - 345)

7tmA_V1bR

7tmA_V1bR: cd15386 (35 - 61)

7tmA_V1bR

7tmA_V1bR: cd15386 (68 - 95)

7tmA_V1bR

7tmA_V1bR: cd15386 (106 - 136)

7tmA_V1bR

7tmA_V1bR: cd15386 (148 - 169)

7tmA_V1bR

7tmA_V1bR: cd15386 (195 - 224)

7tmA_V1bR

7tmA_V1bR: cd15386 (270 - 300)

7tmA_V1bR

7tmA_V1bR: cd15386 (313 - 338)

DUF1856

DUF1856: pfam08983 (358 - 407)

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  • 100
  • 200
  • 300
  • 421 a.a.
蛋白主名 其他名称

vasopressin V1b receptor

AVPR V1b

AVPR V3

V3/V1b pituitary vasopressin receptor

antidiuretic hormone receptor 1b

arginine vasopressin type 1b receptor

vasopressin V3 receptor

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Avpr1b NCBI NCBI:553