2. Gene
  3. Ephb1 - Eph receptor B1 Gene

Ephb1 - Eph receptor B1 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: Elk; Net; Cek6; Elkh; Hek6; 9330129L11; C130099E04Rik

基因 ID: 270190 | 基因类型: protein coding

关于 Ephb1

功能概要

Enables axon guidance receptor activity. Involved in several processes, including dendritic spine morphogenesis; detection of temperature stimulus involved in sensory perception of pain; and negative regulation of satellite cell differentiation. Acts upstream of or within several processes, including axonogenesis; Ephrin Receptor signaling pathway; and optic nerve morphogenesis. Located in several cellular components, including axon; filopodium tip; and membrane raft. Is active in glutamatergic synapse. Is expressed in several structures, including 1st branchial arch; brain; lower urinary tract; sensory organ; and vascular system. Orthologous to human EphB1 (EPH receptor B1). [provided by Alliance of Genome Resources, Apr 2022]

Ephb1 基因产物(2)

mRNA Protein Name
NM_001168296.1 NP_001161768.1 ephrin type-B receptor 1 isoform 2 precursor
NM_173447.3 NP_775623.3 ephrin type-B receptor 1 isoform 1 precursor
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables axon guidance receptor activity IDA
IDA: 通过直接分析推断
11532925 MGI
enables protein binding IPI
IPI: 通过物理相互作用推断
12925710 MGI
enables protein-containing complex binding IPI
IPI: 通过物理相互作用推断
17310244 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within axon guidance IDA
IDA: 通过直接分析推断
11532925 MGI
acts upstream of or within axon guidance IMP
IMP: 通过突变表型推断
12971893 MGI
acts upstream of or within camera-type eye morphogenesis IMP
IMP: 通过突变表型推断
12971893 MGI
involved in cell chemotaxis IMP
IMP: 通过突变表型推断
18057206 MGI
acts upstream of or within central nervous system projection neuron axonogenesis IDA
IDA: 通过直接分析推断
12971893 MGI
acts upstream of or within central nervous system projection neuron axonogenesis IMP
IMP: 通过突变表型推断
12971893 MGI
acts upstream of or within cranial nerve development IMP
IMP: 通过突变表型推断
12971893 MGI
involved in dendritic spine development IMP
IMP: 通过突变表型推断
14691139 MGI
acts upstream of or within dendritic spine morphogenesis IMP
IMP: 通过突变表型推断
17310244 MGI
involved in dendritic spine morphogenesis IMP
IMP: 通过突变表型推断
14691139 MGI
involved in detection of temperature stimulus involved in sensory perception of pain IMP
IMP: 通过突变表型推断
19025592 MGI
acts upstream of or within ephrin receptor signaling pathway IDA
IDA: 通过直接分析推断
17310244 MGI
involved in establishment of cell polarity IMP
IMP: 通过突变表型推断
18057206 MGI
involved in modulation of chemical synaptic transmission IDA
IDA: 通过直接分析推断
19523204 MGI
involved in modulation of chemical synaptic transmission IEP
IEP: 通过表达模式推断
19523204 MGI
involved in modulation of chemical synaptic transmission IMP
IMP: 通过突变表型推断
19523204 MGI
involved in negative regulation of satellite cell differentiation IMP
IMP: 通过突变表型推断
27446912 MGI
involved in negative regulation of skeletal muscle satellite cell proliferation IMP
IMP: 通过突变表型推断
27446912 MGI
involved in neural precursor cell proliferation IMP
IMP: 通过突变表型推断
18057206 MGI
involved in neurogenesis IMP
IMP: 通过突变表型推断
18057206 MGI
acts upstream of or within optic nerve morphogenesis IMP
IMP: 通过突变表型推断
12971893 MGI
involved in positive regulation of synapse assembly IMP
IMP: 通过突变表型推断
14691139 MGI
acts upstream of or within retinal ganglion cell axon guidance IDA
IDA: 通过直接分析推断
12971893 MGI
involved in skeletal muscle satellite cell activation IMP
IMP: 通过突变表型推断
27446912 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in axon IDA
IDA: 通过直接分析推断
16701205 MGI
located in cytoplasm IDA
IDA: 通过直接分析推断
12093895 MGI
located in filopodium tip IDA
IDA: 通过直接分析推断
24305805 MGI
is active in glutamatergic synapse IDA
IDA: 通过直接分析推断
19523204 MGI
is active in glutamatergic synapse IEP
IEP: 通过表达模式推断
19523204 MGI
is active in glutamatergic synapse IMP
IMP: 通过突变表型推断
19523204 MGI
located in membrane IDA
IDA: 通过直接分析推断
12093895 MGI
located in membrane raft IDA
IDA: 通过直接分析推断
15502157 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

ephrin type-B receptor 1

重组 Ephb1 蛋白

目录号 产品名 蛋白编号 纯度
HY-P75747 EphB1 Protein, Mouse (sf9, His-GST) Q8CBF3-1 (M591-A984) ≥95%
HY-P75748 EphB1 Protein, Mouse (HEK293, His) Q8CBF3-1 (M18-L539) ≥95%

相关产品

Pre-clinical Phase
生物活性分子 (2)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-115481 EphB1-IN-1 Inhibitor 99.87% 否
HY-RS04433 EPHB1 Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Ephb1 NCBI NCBI:2047
Macaca mulatta Ephb1 NCBI NCBI:717211
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