STAU2 - staufen double-stranded RNA binding protein 2 Gene

中文名称：诗道芬双链 RNA 结合蛋白 2

种属: Homo sapiens

同用名: 39K2; 39K3

关于 STAU2

功能概要

Staufen 同系物 2 是双链 RNA (dsRNA) 结合蛋白家族的成员，参与将 mRNA 转运和/或定位到不同的亚细胞区室和/或细胞器。这些蛋白质的特征在于存在多个 dsRNA 结合域，这些域是结合具有双链二级结构的 RNA 所必需的。 Staufen homolog 2 与果蝇和人类 Staufen 的相似性分别为 48.5% 和 59.9%。 Staufen 同源物 2 的确切功能尚不清楚，但由于它包含 3 个拷贝的保守 dsRNA 结合域，它可能参与双链 RNA 结合事件。已发现该基因编码不同亚型的几种转录变体。[RefSeq 提供，2009 年 8 月]

Staufen homolog 2 is a member of the family of double-stranded RNA (dsRNA)-binding proteins involved in the transport and/or localization of mRNAs to different subcellular compartments and/or organelles. These proteins are characterized by the presence of multiple dsRNA-binding domains which are required to bind RNAs having double-stranded secondary structures. Staufen homolog 2 shares 48.5% and 59.9% similarity with drosophila and human staufen, respectively. The exact function of Staufen homolog 2 is not known, but since it contains 3 copies of conserved dsRNA binding domain, it could be involved in double-stranded RNA binding events. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2009]