2. Gene
  3. CACYBP - calcyclin binding protein Gene

CACYBP - calcyclin binding protein Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：钙周期蛋白结合蛋白

种属: Homo sapiens

同用名: SIP; GIG5; PNAS-107; S100A6BP

基因 ID: 27101 | 基因类型: protein coding

关于 CACYBP

Cytogenetic location: 1q25.1 Genomic coordinates (GRCh38): 1:174,999,435-175,012,027 (from NCBI)

This gene has 9 transcripts (splice variants) and 240 orthologues. Ubiquitous expression in brain (RPKM 20.4), ovary (RPKM 13.4) and 25 other tissues.

功能概要

该基因编码的蛋白质是钙周期蛋白结合蛋白。它可能参与钙依赖性泛素化和随后的靶蛋白蛋白体降解。它可能充当泛素 E3 复合物中的分子桥，并参与泛素介导的 β-连环蛋白降解。已经为该基因发现了编码不同亚型的两个选择性剪接的转录物变体。[RefSeq 提供，2008 年 7 月]

The protein encoded by this gene is a calcyclin binding protein. It may be involved in calcium-dependent ubiquitination and subsequent proteosomal degradation of target proteins. It probably serves as a molecular bridge in ubiquitin E3 complexes and participates in the ubiquitin-mediated degradation of beta-catenin. Two alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

CACYBP 基因产物(2)

mRNA Protein Name
NM_001007214.1 NP_001007215.1 calcyclin-binding protein isoform 2
NM_014412.3 NP_055227.1 calcyclin-binding protein isoform 1

CACYBP 蛋白结构

Siah-Interact_N

Siah-Interact_N: Siah interacting protein, N terminal (4 - 75)

CS

CS: CS domain (77 - 156)

SGS

SGS: SGS domain (161 - 218)

  • 0
  • 100
  • 200
  • 228 a.a.
蛋白主名 其他名称

calcyclin-binding protein

S100A6-binding protein

CACYBP 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
Intra CACYBP Q9HB71 S100A6 Homo sapiens P06703
FPS
31837246
Intra CACYBP Q9HB71 S100A4 Homo sapiens P26447
FPS
31837246
Intra CACYBP Q9HB71 S100A5 Homo sapiens P33763
FPS
31837246
种属间: 跨种属相互作用 种属内: 同种属相互作用

关联疾病

疾病名称 别名
Neuroblastoma

Nb

Neuroblastoma, Susceptibility To

Neuroblastomas

Central Neuroblastoma
Gastric Cancer

Stomach Cancer

Gastric Carcinoma

Stomach Carcinoma

Gastric Cancer, Somatic

Gastric Neoplasm

Carcinoma Of Stomach

Stomach Neoplasms

Malignant Neoplasm Of Stomach

Gastric Cancer Risk After H. Pylori Infection

Cancer Of The Stomach

Adult Stomach Cancer

Adult Stomach Carcinoma

GASC

Gastric Cancer Intestinal

Gastric Cancers

Gastric Carcinomas

Cancer, Gastric

Stomach Neoplasm

Malignant Neoplasm Of Body Of Stomach

Malignant Tumor Of Lesser Curve Of Stomach

Gastrocarcinoma Of Unspecified Site

Leather Bottle Stomach

Carcinoma Of Fundus Of Stomach

Cancer Of Fundus Of Stomach

Primary Malignant Neoplasm Of Body Of Stomach

Cancer Of Body Of Stomach

Primary Malignant Neoplasm Of Pyloric Antrum

Pyloric Antrum Cancer

Malignant Tumour Of Stomach
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS01817 CACYBP Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Bos taurus CACYBP VGNC VGNC:26693
Macaca mulatta CACYBP VGNC VGNC:70678
Mus musculus CACYBP MGD MGI:1270839
Felis catus CACYBP VGNC VGNC:97371
Rattus norvegicus CACYBP RGD RGD:1303146
Canis familiaris CACYBP VGNC VGNC:55735
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