MOCS3 - molybdenum cofactor synthesis 3 Gene

中文名称：钼辅助因子合成 3

种属: Homo sapiens

同用名: UBA4

基因 ID: 27304 | 基因类型: protein coding

关于 MOCS3

Cytogenetic location: 20q13.13 Genomic coordinates (GRCh38): 20:50,958,818-50,963,929 (from NCBI)

This gene has 1 transcript (splice variant), 195 orthologues and 9 paralogues.

功能概要

钼辅助因子 (MoCo) 是所有钼酶发挥功能所必需的。由该基因编码的蛋白质腺苷酸化并激活钼蝶呤合酶，这是一种生物合成 MoCo 所需的酶。该基因不含内含子。该基因的假基因存在于 14 号染色体上。[RefSeq 提供，2012 年 11 月]

Molybdenum cofactor (MoCo) is necessary for the function of all molybdoenzymes. The protein encoded by this gene adenylates and activates molybdopterin synthase, an Enzyme required for biosynthesis of MoCo. This gene contains no introns. A pseudogene of this gene is present on chromosome 14. [provided by RefSeq, Nov 2012]

MOCS3 基因产物(1)

mRNA	Protein	Name
NM_014484.5	NP_055299.1	adenylyltransferase and sulfurtransferase MOCS3

基因本体论

分子功能
生物过程
细胞组分

分子功能 GO 注释	逻辑证据	参考文献	来源
enables URM1 activating enzyme activity	IDA IDA: 通过直接分析推断	19017811	GOA
enables molybdopterin-synthase sulfurtransferase activity	IDA IDA: 通过直接分析推断	15073332	GOA
enables molybdopterin-synthase sulfurtransferase activity	IMP IMP: 通过突变表型推断	15073332	GOA
enables nucleotidyltransferase activity	IDA IDA: 通过直接分析推断	19017811	GOA
enables protein binding	IPI IPI: 通过物理相互作用推断	18650437	GOA
enables sulfurtransferase activity	IDA IDA: 通过直接分析推断	15910006	GOA
enables sulfurtransferase activity	IMP IMP: 通过突变表型推断	17459099	GOA

生物过程 GO 注释	逻辑证据	参考文献	来源
involved in Mo-molybdopterin cofactor biosynthetic process	IDA IDA: 通过直接分析推断	15073332	GOA
involved in Mo-molybdopterin cofactor biosynthetic process	IMP IMP: 通过突变表型推断	30817134	GOA
involved in molybdopterin cofactor metabolic process	IDA IDA: 通过直接分析推断	18650437	GOA
involved in tRNA thio-modification	IDA IDA: 通过直接分析推断	19017811	GOA
involved in tRNA thio-modification	IMP IMP: 通过突变表型推断	30817134	GOA
involved in tRNA wobble uridine modification	IDA IDA: 通过直接分析推断	19017811	GOA

细胞组分 GO 注释	逻辑证据	参考文献	来源
located in cytoplasm	IDA IDA: 通过直接分析推断	23593335	GOA
located in cytosol	IDA IDA: 通过直接分析推断	15073332	GOA

EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

MOCS3 蛋白结构

ThiF

Rhodanese

0
100
200
300
400
460 a.a.

蛋白主名

其他名称

adenylyltransferase and sulfurtransferase MOCS3

MPT synthase sulfurylase

MOCS3 蛋白互作信息

分类	蛋白名称	蛋白编号	互作蛋白	互作蛋白种属	互作蛋白编号	实验方法	参考文献
种属内	MOCS3	O95396	TARDBP	Homo sapiens	Q13148	Validated Y2H	32814053
种属内	MOCS3	O95396	TARDBP	Homo sapiens	Q13148	Y2H Array	32814053
种属内	MOCS3	O95396	TARDBP	Homo sapiens	Q13148	Y2H Pooling	32814053
种属内	MOCS3	O95396	ATXN1	Homo sapiens	P54253	Y2H Pooling	32814053
种属内	MOCS3	O95396	ATXN1	Homo sapiens	P54253	Validated Y2H	32814053
种属内	MOCS3	O95396	ATXN1	Homo sapiens	P54253	Y2H Array	32814053

种属间: 跨种属相互作用 种属内: 同种属相互作用

关联疾病

疾病名称

别名

Molybdenum Cofactor Deficiency

Combined Molybdoflavoprotein Enzyme Deficiency	Mocod
Combined Deficiency Of Sulfite Oxidase, Xanthine Dehydrogenase, And Aldehyde Oxidase	Combined Deficiency Of Sulfite Oxidase, Xanthine Dehydrogenase And Aldehyde Oxidase
Combined Xanthine Oxidase And Sulfite Oxidase And Aldehyde Oxidase Deficiency	Deficiency Of Molybdenum Cofactor
Deficiency, Molybdenum Cofactor

Molybdenum Cofactor Deficiency, Complementation Group C

MOCODC	Sulfite Oxidase Deficiency Due To Molybdenum Cofactor Deficiency Type C
Molybdenum Cofactor Deficiency C	Molybdenum Cofactor Deficiency Type C
Combined Deficiency Of Sulfite Oxidase, Xanthine Dehydrogenase And Aldehyde Oxidase Type C	Mocod Type C
Molybdenum Cofactor Deficiency Complementation Group C	Deficiency, Molybdenum Cofactor, Complementation Group C

Sulfite Oxidase Deficiency, Isolated

Sulfite Oxidase Deficiency	Sulfocysteinuria
Isolated Sulfite Oxidase Deficiency	ISOD
Encephalopathy Due To Sulfite Oxidase Deficiency

Molybdenum Cofactor Deficiency, Complementation Group A

MOCODA	Sulfite Oxidase Deficiency Due To Molybdenum Cofactor Deficiency Type A
Molybdenum Cofactor Deficiency A	Molybdenum Cofactor Deficiency Type A
Combined Deficiency Of Sulfite Oxidase, Xanthine Dehydrogenase And Aldehyde Oxidase Type A	Mocod Type A
Combined Deficiency Of Sulfite Oxidase, Xanthine Dehydrogenase, And Aldehyde Oxidase	Sulfite Oxidase, Xanthine Dehydrogenase, And Aldehyde Oxidase, Combined Deficiency Of
Molybdenum Cofactor Deficiency Complementation Group A	Molybdenum Cofactor Deficiency, Type A
Deficiency, Molybdenum Cofactor, Complementation Group A

Molybdenum Cofactor Deficiency, Complementation Group B

MOCODB	Sulfite Oxidase Deficiency Due To Molybdenum Cofactor Deficiency Type B
Molybdenum Cofactor Deficiency B	Molybdenum Cofactor Deficiency Type B
Combined Deficiency Of Sulfite Oxidase, Xanthine Dehydrogenase And Aldehyde Oxidase Type B	Mocod Type B
Molybdenum Cofactor Deficiency Complementation Group B	Deficiency, Molybdenum Cofactor, Complementation Group B

Neu-Laxova Syndrome 2

NLS2

Encephalomalacia

疾病名称	别名
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Cat. No.	产品名	作用方式	纯度	是否罕见病
HY-RS08582	MOCS3 Human Pre-designed siRNA Set A	Pre-designed Sets	/	否

直系同源

种属	基因名	来源	基因 ID
Canis familiaris	MOCS3	VGNC	VGNC:43307
Bos taurus	MOCS3	VGNC	VGNC:31549
Macaca mulatta	MOCS3	VGNC	VGNC:74772
Rattus norvegicus	MOCS3	RGD	RGD:1307044
Mus musculus	MOCS3	MGD	MGI:1916622
Felis catus	MOCS3	VGNC	VGNC:63550

MedChemExpress (MCE) 只为有资质的科研机构、医药企业基于科学研究或药证申报的用途提供医药研发服务，不为任何个人或者非科研性质的、非用于药证申报使用等其他用途提供服务。	站点地图隐私声明
沪ICP备15051369号-4 上海工商沪公网安备31011502019417 沪(浦)应急管危经许[2021]201709(QFYS) 营业执照（三证合一）
Copyright © 2013-2024 MedChemExpress. All Rights Reserved.

MedChemExpress (MCE) 只为有资质的科研机构、医药企业基于科学研究或药证申报的用途提供医药研发服务，不为任何个人或者非科研性质的、非用于药证申报使用等其他用途提供服务。

站点地图隐私声明

沪ICP备15051369号-4

上海工商

沪公网安备31011502019417

沪(浦)应急管危经许[2021]201709(QFYS)

营业执照（三证合一）

MOCS3 - molybdenum cofactor synthesis 3 Gene

关于 MOCS3

功能概要

MOCS3 基因产物(1)

MOCS3 蛋白结构

MOCS3 蛋白互作信息

关联疾病

直系同源

热门区域

A

B

C

F

G

H

J

L

N

Q

S

T

X

Y

Z

姓名
邮箱 *

Sorry, but the email address you supplied was invalid.

MOCS3 - molybdenum cofactor synthesis 3 Gene

关于 MOCS3

功能概要

MOCS3 基因产物(1)

MOCS3 蛋白结构

MOCS3 蛋白互作信息

关联疾病

相关产品

直系同源

热门区域

A

B

C

F

G

H

J

L

N

Q

S

T

X

Y

Z