2. Gene
  3. GMPR - guanosine monophosphate reductase Gene

GMPR - guanosine monophosphate reductase Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：鸟苷一磷酸还原酶

种属: Homo sapiens

同用名: GMPR1; GMPR 1

基因 ID: 2766 | 基因类型: protein coding

关于 GMPR

Cytogenetic location: 6p22.3 Genomic coordinates (GRCh38): 6:16,238,587-16,295,549 (from NCBI)

This gene has 4 transcripts (splice variants), 208 orthologues and 3 paralogues. Broad expression in prostate (RPKM 33.0), testis (RPKM 29.5) and 19 other tissues.

功能概要

该基因编码一种酶，该酶催化 GMP 向 IMP 的不可逆和 NADPH 依赖性还原脱氨作用。该蛋白质还在游离细胞内碱基和嘌呤核苷的再利用中发挥作用。[RefSeq 提供，2009 年 10 月]

This gene encodes an Enzyme that catalyzes the irreversible and NADPH-dependent reductive deamination of GMP to IMP. The protein also functions in the re-utilization of free intracellular bases and purine nucleosides.[provided by RefSeq, Oct 2009]

GMPR 基因产物(1)

mRNA Protein Name
NM_006877.4 NP_006868.3 GMP reductase 1

GMPR 蛋白结构

IMPDH

IMPDH: IMP dehydrogenase / GMP reductase domain (9 - 341)

  • 0
  • 100
  • 200
  • 300
  • 345 a.a.
蛋白主名 其他名称

GMP reductase 1

guanine monophosphate reductase

重组 GMPR 蛋白

目录号 产品名 蛋白编号 纯度
HY-P70955 GMPR Protein, Human (HEK293, His) AAH08281.1 (M1-S345) ≥95%
HY-P75791 GMPR Protein, Human (His) P36959/NP_006868.3 (M1-S345) ≥95%

关联疾病

疾病名称 别名
Viral Gastritis
Cystathioninuria

Cystathionase Deficiency

Gamma-Cystathionase Deficiency

Cystathione Gamma-Lyase Deficiency Syndrome

Cystathionine Gamma-Lyase Deficiency Syndrome

CSTNU
Fumarase Deficiency

Fumaric Aciduria

FMRD

Fumarate Hydratase Deficiency

Deficiency, Fumarase
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (2)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS05526 GMPR Human Pre-designed siRNA Set A Pre-designed Sets / 否
HY-RS05527 GMPR2 Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Mus musculus GMPR MGD MGI:1913605
Macaca mulatta GMPR VGNC VGNC:73082
Rattus norvegicus GMPR RGD RGD:70980
Felis catus GMPR VGNC VGNC:62612
Canis familiaris GMPR VGNC VGNC:41294
Bos taurus GMPR VGNC VGNC:29442
Others GMPR NCBI
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