1. Gene
  2. SSX7 - SSX family member 7 Gene

SSX7 - SSX family member 7 Gene

中文名称:SSX 家族成员 7

种属: Homo sapiens

基因 ID: 280658 | 基因类型: protein coding

关于 SSX7

Cytogenetic location: Xp11.22 Genomic coordinates (GRCh38): X:52,644,061-52,654,900 (from NCBI)

This gene has 1 transcript (splice variant), 104 orthologues and 7 paralogues. Low expression observed in reference dataset.

功能概要

该基因的产物属于高度同源的滑膜肉瘤 X (SSX) 断点蛋白家族。这些蛋白质可能起到转录抑制因子的作用。它们还能够在癌症患者中引发自发的体液和细胞免疫反应,并且是基于癌症疫苗的免疫疗法的潜在有用靶点。 SSX1、SSX2 和 SSX4 基因参与了所有滑膜肉瘤中典型的 t (X;18) 易位。该基因似乎不参与此类染色体易位。[RefSeq 提供,2008 年 7 月]

The product of this gene belongs to the family of highly homologous synovial sarcoma X (SSX) breakpoint proteins. These proteins may function as transcriptional repressors. They are also capable of eliciting spontaneously humoral and cellular immune responses in Cancer patients, and are potentially useful targets in Cancer vaccine-based immunotherapy. SSX1, SSX2 and SSX4 genes have been involved in the t(X;18) translocation characteristically found in all synovial sarcomas. This gene appears not to be involved in this type of chromosome translocation. [provided by RefSeq, Jul 2008]

SSX7 基因产物(1)

mRNA Protein Name
NM_173358.2 NP_775494.1 protein SSX7
基因本体论
  • 分子功能
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
32296183 GOA
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断

SSX7 蛋白结构

SSXRD

SSXRD: SSXRD motif (155 - 188)

  • 0
  • 100
  • 188 a.a.
蛋白主名 其他名称

protein SSX7

synovial sarcoma, X breakpoint 7

SSX7 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
Intra SSX7 Q7RTT5 LRRC45 Homo sapiens Q96CN5
Validated Y2H
32296183
Intra SSX7 Q7RTT5 LRRC45 Homo sapiens Q96CN5
Y2H Prey Pooling
32296183
Intra SSX7 Q7RTT5 CIB1 Homo sapiens Q99828
Validated Y2H
32296183
Intra SSX7 Q7RTT5 CIB1 Homo sapiens Q99828
Y2H Array
32296183
Intra SSX7 Q7RTT5 CIB1 Homo sapiens Q99828
Y2H Prey Pooling
32296183
Intra SSX7 Q7RTT5 SERTAD1 Homo sapiens Q9UHV2
Y2H Prey Pooling
32296183
Intra SSX7 Q7RTT5 SERTAD1 Homo sapiens Q9UHV2
Validated Y2H
32296183
Intra SSX7 Q7RTT5 DNAAF11 Homo sapiens Q86X45
Validated Y2H
32296183
种属间: 跨种属相互作用 种属内: 同种属相互作用