1. Gene
  2. TMEM102 - transmembrane protein 102 Gene

TMEM102 - transmembrane protein 102 Gene

中文名称:跨膜蛋白 102

种属: Homo sapiens

同用名: CBAP

基因 ID: 284114 | 基因类型: protein coding

关于 TMEM102

Cytogenetic location: 17p13.1 Genomic coordinates (GRCh38): 17:7,435,435-7,437,679 (from NCBI)

This gene has 2 transcripts (splice variants), 1 gene allele, 97 orthologues and 9 paralogues. Ubiquitous expression in colon (RPKM 3.0), adrenal (RPKM 2.7) and 24 other tissues.

功能概要

参与调节参与细胞凋亡信号通路的线粒体外膜透化;对细胞因子的反应;和信号转导。在 T 细胞迁移的正调节和细胞粘附的正调节的上游或内部起作用。位于细胞表面。部分含蛋白质复合物。 [由基因组资源联盟提供,2022 年 4 月]

Involved in regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway; response to cytokine; and signal transduction. Acts upstream of or within positive regulation of T cell migration and positive regulation of cell adhesion. Located in cell surface. Part of protein-containing complex. [provided by Alliance of Genome Resources, Apr 2022]

TMEM102 基因产物(2)

mRNA Protein Name
NM_001320444.1 NP_001307373.1 transmembrane protein 102
NM_178518.3 NP_848613.1 transmembrane protein 102
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
17828305 GOA
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within positive regulation of T cell migration IDA
IDA: 通过直接分析推断
23620790 GOA
acts upstream of or within positive regulation of cell adhesion IDA
IDA: 通过直接分析推断
23620790 GOA
involved in regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway IDA
IDA: 通过直接分析推断
17828305 GOA
involved in response to cytokine IDA
IDA: 通过直接分析推断
17828305 GOA
involved in signal transduction IDA
IDA: 通过直接分析推断
17828305 GOA
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in cell surface IDA
IDA: 通过直接分析推断
17828305 GOA
part of protein-containing complex IDA
IDA: 通过直接分析推断
23620790 GOA
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断

TMEM102 蛋白结构

Mab-21

Mab-21: Mab-21 protein (307 - 456)

  • 0
  • 100
  • 200
  • 300
  • 400
  • 508 a.a.
蛋白主名 其他名称

transmembrane protein 102

common beta-chain associated protein

TMEM102 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
Intra TMEM102 Q8N9M5 SLC12A4 Homo sapiens Q9UP95
Validated Y2H
32296183
种属间: 跨种属相互作用 种属内: 同种属相互作用

直系同源

种属 基因名 来源 基因 ID
Canis familiaris TMEM102 VGNC VGNC:49837
Macaca mulatta TMEM102 VGNC VGNC:99302
Rattus norvegicus TMEM102 RGD RGD:1559450
Bos taurus TMEM102 VGNC VGNC:35943
Mus musculus TMEM102 MGD MGI:1921591
Felis catus TMEM102 VGNC VGNC:66254