2. Gene
  3. SCAI - suppressor of cancer cell invasion Gene

SCAI - suppressor of cancer cell invasion Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：癌细胞侵袭抑制因子

种属: Homo sapiens

同用名: NET40; C9orf126

基因 ID: 286205 | 基因类型: protein coding

关于 SCAI

Cytogenetic location: 9q33.3 Genomic coordinates (GRCh38): 9:124,942,608-125,143,528 (from NCBI)

This gene has 7 transcripts (splice variants) and 207 orthologues. Ubiquitous expression in brain (RPKM 4.6), lung (RPKM 2.0) and 24 other tissues.

功能概要

该基因编码细胞迁移的调节因子。编码的蛋白质似乎在 RhoA (Ras 同系物基因家族，成员 A) -Dia1 (透明同系物 1) 信号转导通路中起作用。已经描述了选择性剪接的转录物变体。[RefSeq 提供，2010 年 2 月]

This gene encodes a regulator of cell migration. The encoded protein appears to function in the RhoA (Ras homolog gene family, member A)-Dia1 (diaphanous homolog 1) signal transduction pathway. Alternatively spliced transcript variants have been described. [provided by RefSeq, Feb 2010]

SCAI 基因产物(2)

mRNA Protein Name
NM_001144877.3 NP_001138349.1 protein SCAI isoform 2
NM_173690.5 NP_775961.2 protein SCAI isoform 1
基因本体论
  • 分子功能
  • 生物过程
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
19350017 GOA
enables transcription corepressor activity IMP
IMP: 通过突变表型推断
19350017 GOA
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in negative regulation of cell migration IMP
IMP: 通过突变表型推断
19350017 GOA
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

SCAI 蛋白结构

SCAI

SCAI: Protein SCAI (63 - 558)

  • 0
  • 100
  • 200
  • 300
  • 400
  • 500
  • 606 a.a.
蛋白主名 其他名称

protein SCAI

suppressor of cancer cell invasion protein

SCAI 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
种属内
SCAI Q8N9R8 OGT Homo sapiens O15294-3
Y2H Prey Pooling
32296183
种属内
SCAI Q8N9R8 OGT Homo sapiens O15294-3
Y2H Array
32296183
种属内
SCAI Q8N9R8 CDIPT Homo sapiens O14735
Y2H Array
32296183
种属内
SCAI Q8N9R8 CDIPT Homo sapiens O14735
Y2H Prey Pooling
32296183
种属内
SCAI Q8N9R8 SOX7 Homo sapiens Q9BT81
Y2H Prey Pooling
32296183
种属内
SCAI Q8N9R8 SOX7 Homo sapiens Q9BT81
Validated Y2H
32296183
种属内
SCAI Q8N9R8 SOX7 Homo sapiens Q9BT81
Y2H Array
32296183
种属间: 跨种属相互作用 种属内: 同种属相互作用

SCAI 抗体

目录号 产品名 应用 反应物种
HY-P82161 SCAI Antibody (YA1906) WB, IHC-F, IHC-P, ICC/IF Human, Mouse, Rat

关联疾病

疾病名称 别名
Vertebral Artery Insufficiency

Vertebral Artery Syndrome
Lateral Myocardial Infarction
Spinocerebellar Ataxia, X-Linked 2

Scax2

X-Linked Spinocerebellar Ataxia 2

Cerebellar Ataxia With Extrapyramidal Involvement Early-Onset

Cerebellar Ataxia With Extrapyramidal Involvement, Early-Onset

Spinocerebellar Ataxia X-Linked Type 2
Subclavian Steal Syndrome

Subclavian Artery Stenosis

Subclavian Steal Phenomenon

Subclavian Steal Steno-Occlusive Disease

Subclavian Steal
Thrombophilia, X-Linked, Due To Factor Ix Defect

THPH8

Deep Venous Thrombosis, Protection Against

X-Linked Thrombophilia Due To Factor Ix Defect

Thrombophilia, X-Linked, Due To Factor 9 Defect

Thrombophilia 8, X-Linked, Due To Factor Ix Defect
Hyperinsulinemic Hypoglycemia, Familial, 4

Hyperinsulinism Due To Glutamodehydrogenase Deficiency

HHF4

Familial Hyperinsulinemic Hypoglycemia 4

Hyperinsulinemic Hypoglycemia Due To Short Chain 3-Hydroxylacyl-Coa Dehydrogenase Deficiency

Hyperinsulinism Due To Schad Deficiency

Hyperinsulinism Due To Short Chain 3-Hydroxylacyl-Coa Dehydrogenase Deficiency

Congenital Hyperinsulinism

Schad Deficiency

Persistent Hyperinsulinemic Hypoglycemia Of Infancy

Phhi

3-Hydroxyacyl-Coa Dehydrogenase Deficiency
Left Bundle Branch Hemiblock

Left Bundle Branch Block

Left Bundle-Branch Block
Aortic Valve Insufficiency

Aortic Regurgitation

Rheumatic Aortic Regurgitation

Aortic Insufficiency

Rheumatic Aortic Insufficiency

Rheumatic Aortic Valve Insufficiency

Aortic Incompetence

Corrigan'S Disease

Rheumatic Aortic Valve Regurgitation

Aortic Valve Incompetency

Ai - [Aortic Incompetence]

Incompetent Aortic Valve

Ar - [Aortic Regurgitation]

Calcific Aortic Valve Regurgitation

Myxomatous Aortic Valve Regurgitation

Annular Incompetency Of Aortic Valve

Austin Flint Murmur

Flint Murmur

Rheumatic Aortic Incompetence

Rheumatic Ai - [Aortic Insufficiency]
Patent Foramen Ovale

Atrial Septal Defect Within Oval Fossa

Foramen Ovale Patent

Ostium Secundum Atrial Septal Defect

Atrial Septal Defect, Ostium Secundum Type

Foramen Ovale, Patent

Defect, Patent Or Persistent, Ostium Secundum

Ostium Secundum Type Atrial Septal Defect

Persistent Ostium Secundum

Asd Ostium Secundum Type

Ostium Secundum Asd

Osasd

Asd, Ostium Secundum Type

Pfo - [Patent Foramen Ovale]

Open Foramen Ovale

Open Oval Foramen

Persistent Foramen Ovale

Secundum Atrial Septal Defect
Lipoprotein Quantitative Trait Locus

Coronary Artery Disease

Coronary Artery Anomaly

Coronary Artery Disease, Susceptibility To

Myocardial Ischemia

Congenital Anomaly Of Coronary Artery

Coronary Arteriosclerosis

Coronary Disease

Coronary Heart Disease

Coronary Artery Disorder

LPAQTL

Lpa Deficiency, Congenital

Coronary Artery Abnormality

Coronary Artery Anomaly, Congenital

Chd

Coronary Syndrome

Congenital Malformations Of Coronary Vessels

Malformation Of Coronary Vessels

Congenital Coronary Artery Anomaly

Congenital Coronary Artery Deformity

Congenital Coronary Artery Disorder

Abnormal Coronary Artery

Congenital Coronary Artery Malposition

Congenital Coronary Disease

Congenital Anomaly Of Coronary Arteries
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS12477 SCAI Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Rattus norvegicus SCAI RGD RGD:1594720
Felis catus SCAI VGNC VGNC:102978
Mus musculus SCAI MGD MGI:2443716
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