2. Gene
  3. Serpinf1 - serpin family F member 1 Gene

Serpinf1 - serpin family F member 1 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Rattus norvegicus

同用名: Pedf; Dmrs91

基因 ID: 287526 | 基因类型: protein coding

关于 Serpinf1

功能概要

Predicted to enable serine-type endopeptidase inhibitor activity. Involved in several processes, including cellular response to glucose stimulus; cellular response to lipid; and short-term memory. Located in several cellular components, including axon hillock; basement membrane; and perinuclear region of cytoplasm. Used to study Alzheimer's disease; middle cerebral artery infarction; and type 2 diabetes mellitus. Biomarker of endometriosis; obesity; portal hypertension; retinal disease (multiple); and type 2 diabetes mellitus. Human ortholog(s) of this gene implicated in several diseases, including brain edema; eye disease (multiple); leukostasis; non-alcoholic steatohepatitis; and osteogenesis imperfecta type 6. Orthologous to human SERPINF1 (serpin family F member 1). [provided by Alliance of Genome Resources, Apr 2022]

Serpinf1 基因产物(1)

mRNA Protein Name
NM_177927.2 NP_808788.1 pigment epithelium-derived factor precursor
基因本体论
  • 生物过程
  • 细胞组分
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in cellular response to cobalt ion IEP
IEP: 通过表达模式推断
21922517 RGD
involved in cellular response to dexamethasone stimulus IEP
IEP: 通过表达模式推断
15051476 RGD
involved in cellular response to glucose stimulus IEP
IEP: 通过表达模式推断
19107574 RGD
involved in cellular response to retinoic acid IEP
IEP: 通过表达模式推断
15051476 RGD
involved in kidney development IEP
IEP: 通过表达模式推断
17497179 RGD
involved in negative regulation of endothelial cell migration IMP
IMP: 通过突变表型推断
11792807 RGD
involved in negative regulation of gene expression IMP
IMP: 通过突变表型推断
21922517 RGD
involved in ovulation cycle IEP
IEP: 通过表达模式推断
23466670 RGD
involved in positive regulation of neuron projection development IMP
IMP: 通过突变表型推断
23825416 RGD
involved in response to acidic pH IEP
IEP: 通过表达模式推断
19575033 RGD
involved in response to arsenic-containing substance IEP
IEP: 通过表达模式推断
23229538 RGD
involved in response to organic cyclic compound IDA
IDA: 通过直接分析推断
10360224 RGD
involved in response to peptide IDA
IDA: 通过直接分析推断
10423332 RGD
involved in retina development in camera-type eye IEP
IEP: 通过表达模式推断
21738387 RGD
involved in short-term memory IDA
IDA: 通过直接分析推断
17073149 RGD
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in axon IDA
IDA: 通过直接分析推断
10411342 RGD
located in axon hillock IDA
IDA: 通过直接分析推断
10411342 RGD
located in basement membrane IDA
IDA: 通过直接分析推断
15616035 RGD
located in extracellular region IDA
IDA: 通过直接分析推断
19575033 RGD
located in extracellular space IDA
IDA: 通过直接分析推断
17653050 RGD
located in neuronal cell body IDA
IDA: 通过直接分析推断
10411342 RGD
located in perinuclear region of cytoplasm IDA
IDA: 通过直接分析推断
10411342 RGD
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

pigment epithelium-derived factor

alpha-2 antiplasmin

serine (or cysteine) peptidase inhibitor, clade F, member 1

serine (or cysteine) proteinase inhibitor, clade F), member 1

serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1

sserpi

重组 Serpinf1 蛋白

目录号 产品名 蛋白编号 纯度
HY-P74557 Serpin F1 Protein, Rat (HEK293, His) Q80ZA3/NP_808788.1 (Q20-T418) ≥95%

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS12725 SERPINF1 Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Serpinf1 NCBI NCBI:5176
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