2. Gene
  3. Fcgr2b - Fc gamma receptor 2B Gene

Fcgr2b - Fc gamma receptor 2B Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Rattus norvegicus

同用名: CD32; FCRII; Fcgr2; FcgammaRIIB2

基因 ID: 289211 | 基因类型: protein coding

关于 Fcgr2b

功能概要

Enables IgG binding activity. Involved in several processes, including cellular response to amyloid-beta; cellular response to lipopolysaccharide; and negative regulation of neutrophil apoptotic process. Located in cell surface; membrane raft; and recycling endosome. Human ortholog(s) of this gene implicated in several diseases, including autoimmune disease (multiple); dengue disease (multiple); hematologic Cancer (multiple); leukopenia (multiple); and malaria (multiple). Orthologous to several human genes including FCGR2B (Fc fragment of IgG receptor IIb). [provided by Alliance of Genome Resources, Apr 2022]

Fcgr2b 基因产物(1)

mRNA Protein Name
NM_175756.3 NP_786932.2 low affinity immunoglobulin gamma Fc region receptor II
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables IgG binding IDA
IDA: 通过直接分析推断
7590913 RGD
enables immunoglobulin binding IDA
IDA: 通过直接分析推断
18295888 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in cellular response to amyloid-beta IMP
IMP: 通过突变表型推断
23921129 RGD
involved in cellular response to lipopolysaccharide IEP
IEP: 通过表达模式推断
19106808 RGD
involved in endocytic recycling IDA
IDA: 通过直接分析推断
17680646 RGD
involved in immune complex clearance IDA
IDA: 通过直接分析推断
17680646 RGD
involved in negative regulation of neutrophil apoptotic process IMP
IMP: 通过突变表型推断
19106808 RGD
involved in positive regulation of response to endoplasmic reticulum stress IMP
IMP: 通过突变表型推断
23921129 RGD
involved in receptor-mediated endocytosis IDA
IDA: 通过直接分析推断
17680646 RGD
involved in regulation of endoplasmic reticulum stress-induced neuron intrinsic apoptotic signaling pathway IMP
IMP: 通过突变表型推断
23921129 RGD
involved in response to estradiol IEP
IEP: 通过表达模式推断
21774811 RGD
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in cell surface IDA
IDA: 通过直接分析推断
18295888 RGD
located in recycling endosome IDA
IDA: 通过直接分析推断
17680646 RGD
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

low affinity immunoglobulin gamma Fc region receptor II

low affinity immunoglobulin gamma Fc region receptor II-b

FC-gamma RII

Fc fragment of IgG receptor IIb

Fc fragment of IgG, low affinity IIb, receptor

Fc gamma receptor IIb

Fc receptor, IgG, low affinity IIb

igG Fc receptor II beta

重组 Fcgr2b 蛋白

目录号 产品名 蛋白编号 纯度
HY-P76235 Fc gamma RIIB/CD32b Protein, Rat (HEK293, His) Q63203 (H32-P212) ≥95%

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS04829 FCGR2B Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Fcgr2b NCBI NCBI:2213
Macaca fascicularis Fcgr2b NCBI NCBI:102139530
Mus musculus Fcgr2b NCBI NCBI:14130
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