FHOD1 - formin homology 2 domain containing 1 Gene

中文名称：含形式同源 2 结构域 1

种属: Homo sapiens

同用名: FHOS

关于 FHOD1

功能概要

该基因编码的蛋白质是甲醛/透明蛋白质家族的成员。该基因普遍表达，但在脾脏中大量存在。编码的蛋白质与 Formin 同源 (FH) 1 和 FH2 结构域内的透明蛋白和福明蛋白具有序列同源性。它还包含一个卷曲螺旋结构域、一个胶原样结构域、两个核定位信号和几个潜在的 PKC 和 PKA 磷酸化位点。它主要是细胞质蛋白，在多种人类细胞系中表达。可变剪接导致多个转录本变体。[RefSeq 提供，2015 年 12 月]

This gene encodes a protein which is a member of the formin/diaphanous family of proteins. The gene is ubiquitously expressed but is found in abundance in the spleen. The encoded protein has sequence homology to diaphanous and formin proteins within the Formin Homology (FH)1 and FH2 domains. It also contains a coiled-coil domain, a collagen-like domain, two nuclear localization signals, and several potential PKC and PKA phosphorylation sites. It is a predominantly cytoplasmic protein and is expressed in a variety of human cell lines. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2015]