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  2. Rab7a - RAB7A, member RAS oncogene family Gene

Rab7a - RAB7A, member RAS oncogene family Gene

种属: Rattus norvegicus

同用名: Rab7

基因 ID: 29448 | 基因类型: protein coding

关于 Rab7a

功能概要

Enables GDP binding activity; GTP binding activity; and small GTPase binding activity. Involved in bone resorption. Located in alveolar lamellar body and late endosome. Is anchored component of synaptic vesicle membrane. Human ortholog(s) of this gene implicated in Charcot-Marie-Tooth disease type 2B. Orthologous to human RAB7A (RAB7A, member Ras oncogene family). [provided by Alliance of Genome Resources, Apr 2022]

Rab7a 基因产物(1)

mRNA Protein Name
NM_023950.4 NP_076440.1 ras-related protein Rab-7a
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables GDP binding IDA
IDA: 通过直接分析推断
16040606 RGD
enables GTP binding IDA
IDA: 通过直接分析推断
16040606 RGD
enables protein binding IPI
IPI: 通过物理相互作用推断
15186776 RGD
enables small GTPase binding IPI
IPI: 通过物理相互作用推断
16040606 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in bone resorption IMP
IMP: 通过突变表型推断
11514537 RGD
involved in synaptic vesicle recycling via endosome EXP
EXP: 通过实验结果推断
29950309 RGD
involved in synaptic vesicle recycling via endosome IDA
IDA: 通过直接分析推断
29950309 RGD
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in alveolar lamellar body IDA
IDA: 通过直接分析推断
7868367 RGD
located in late endosome IDA
IDA: 通过直接分析推断
19337031 RGD
is active in presynaptic endosome IDA
IDA: 通过直接分析推断
29950309 RGD
is active in presynaptic endosome IMP
IMP: 通过突变表型推断
31074746 RGD
is active in synaptic vesicle membrane EXP
EXP: 通过实验结果推断
20926670 RGD
is active in synaptic vesicle membrane IDA
IDA: 通过直接分析推断
20926670 RGD
is active in synaptic vesicle membrane IMP
IMP: 通过突变表型推断
20926670 RGD
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

ras-related protein Rab-7a

RAB7, member RAS oncogene family

ras-related protein BRL-RAS

ras-related protein p23

重组 Rab7a 蛋白

目录号 产品名 蛋白编号 纯度
HY-P75998 RAB7A Protein, Rat (His,solution) P09527 (M1-C207) ≥95%

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Rab7a NCBI NCBI:7879