1. Gene
  2. PRMT6 - protein arginine methyltransferase 6 Gene

PRMT6 - protein arginine methyltransferase 6 Gene

中文名称:蛋白质精氨酸甲基转移酶 6

种属: Rattus norvegicus

同用名: Hrmt1l6

基因 ID: 295384 | 基因类型: protein coding

关于 PRMT6

Primary_assembly 2: 197,927,220-197,933,648 reverse strand.mRatBN7.2:CM026975.1

This gene has 1 transcript (splice variant), 166 orthologues, 10 paralogues and is associated with 2 phenotypes. Biased expression in Thymus (RPKM 33.4), Spleen (RPKM 33.1) and 9 other tissues.

功能概要

预测该基因编码的蛋白可启动染色质结合活性;组蛋白结合活性;和蛋白质-精氨酸 N-甲基转移酶活性。预计参与氮化合物代谢过程的负调控;蛋白质甲基化;和线粒体组织的调节。预计在多个过程的上游或内部起作用,包括细胞衰老;组蛋白 H3-R2 甲基化;氮化合物代谢过程的负调控。预测位于核仁和核质中。与人类 PRMT6(蛋白质精氨酸甲基转移酶 6)同源。 [由基因组资源联盟提供,2022 年 4 月]

Predicted to enable chromatin binding activity; histone binding activity; and protein-arginine N-methyltransferase activity. Predicted to be involved in negative regulation of nitrogen compound metabolic process; protein methylation; and regulation of mitochondrion organization. Predicted to act upstream of or within several processes, including cellular senescence; histone H3-R2 methylation; and negative regulation of nitrogen compound metabolic process. Predicted to be located in nucleolus and nucleoplasm. Orthologous to human PRMT6 (protein arginine methyltransferase 6). [provided by Alliance of Genome Resources, Apr 2022]

PRMT6 基因产物(2)

mRNA Protein Name
NM_001393859.1 NP_001380788.1 protein arginine N-methyltransferase 6
NM_001393858.1 NP_001380787.1 protein arginine N-methyltransferase 6

PRMT6 蛋白结构

AdoMet_MTases

AdoMet_MTases: cd02440 (84 - 184)

  • 0
  • 100
  • 200
  • 300
  • 375 a.a.
蛋白主名 其他名称

protein arginine N-methyltransferase 6

HMT1 hnRNP methyltransferase-like 6

直系同源

种属 基因名 来源 基因 ID
Homo sapiens PRMT6 NCBI NCBI:55170