2. Gene
  3. GTF3C2 - general transcription factor IIIC subunit 2 Gene

GTF3C2 - general transcription factor IIIC subunit 2 Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：一般转录因子 IIIC 亚基 2

种属: Homo sapiens

同用名: TF3C-beta; TFIIIC110; TFIIIC-BETA

基因 ID: 2976 | 基因类型: protein coding

关于 GTF3C2

Cytogenetic location: 2p23.3 Genomic coordinates (GRCh38): 2:27,325,854-27,356,764 (from NCBI)

This gene has 13 transcripts (splice variants) and 196 orthologues. Ubiquitous expression in thyroid (RPKM 13.6), skin (RPKM 10.5) and 25 other tissues.

功能概要

有助于 DNA 结合活性。参与 RNA 聚合酶 III 的转录。位于核质中。转录因子 TFIIIC 复合体的一部分。 [由基因组资源联盟提供，2022 年 4 月]

Contributes to DNA binding activity. Involved in transcription by RNA polymerase III. Located in nucleoplasm. Part of transcription factor TFIIIC complex. [provided by Alliance of Genome Resources, Apr 2022]

GTF3C2 基因产物(17)

mRNA Protein Name
NM_001035521.3 NP_001030598.1 general transcription factor 3C polypeptide 2 isoform b
NM_001318909.4 NP_001305838.2 general transcription factor 3C polypeptide 2 isoform b
NM_001388380.3 NP_001375309.2 general transcription factor 3C polypeptide 2 isoform b
NM_001394503.1 NP_001381432.1 general transcription factor 3C polypeptide 2 isoform b
NM_001394504.1 NP_001381433.1 general transcription factor 3C polypeptide 2 isoform b
NM_001394505.1 NP_001381434.1 general transcription factor 3C polypeptide 2 isoform b
NM_001394506.1 NP_001381435.1 general transcription factor 3C polypeptide 2 isoform b
NM_001394507.1 NP_001381436.1 general transcription factor 3C polypeptide 2 isoform b
NM_001394508.1 NP_001381437.1 general transcription factor 3C polypeptide 2 isoform b
NM_001394509.1 NP_001381438.1 general transcription factor 3C polypeptide 2 isoform b
NM_001394510.1 NP_001381439.1 general transcription factor 3C polypeptide 2 isoform b
NM_001394511.1 NP_001381440.1 general transcription factor 3C polypeptide 2 isoform b
NM_001394512.1 NP_001381441.1 general transcription factor 3C polypeptide 2 isoform d
NM_001394514.1 NP_001381443.1 general transcription factor 3C polypeptide 2 isoform e
NM_001394515.1 NP_001381444.1 general transcription factor 3C polypeptide 2 isoform f
NM_001394516.1 NP_001381445.1 general transcription factor 3C polypeptide 2 isoform g
NM_001521.4 NP_001512.1 general transcription factor 3C polypeptide 2 isoform b
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
contributes to DNA binding IDA
IDA: 通过直接分析推断
17409385 GOA
enables RNA polymerase III general transcription initiation factor activity IDA
IDA: 通过直接分析推断
17409385 GOA
enables protein binding IPI
IPI: 通过物理相互作用推断
17409385 GOA
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in transcription by RNA polymerase III IDA
IDA: 通过直接分析推断
17409385 GOA
细胞组分 GO 注释 逻辑证据 参考文献 来源
part of transcription factor TFIIIC complex IDA
IDA: 通过直接分析推断
17409385 GOA
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

GTF3C2 蛋白结构

WD40

WD40: WD domain, G-beta repeat (607 - 642)

  • 0
  • 200
  • 400
  • 600
  • 800
  • 911 a.a.
蛋白主名 其他名称

general transcription factor 3C polypeptide 2

TFIIIC 110 kDa subunit

关联疾病

疾病名称 别名
Paraphimosis
Proprotein Convertase 1/3 Deficiency

Obesity Due To Prohormone Convertase I Deficiency

Obesity With Impaired Prohormone Processing

Obesity And Endocrinopathy Due To Impaired Processing Of Prohormones

Pci Deficiency

Proprotein Convertase 1 3 Deficiency

Endocrinopathy Due To Proprotein Convertase 1/3 Deficiency

Proprotein Convertase 1 Deficiency

PC1 DEFICIENCY
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS05907 GTF3C2 Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Canis familiaris GTF3C2 VGNC VGNC:41552
Mus musculus GTF3C2 MGD MGI:1919002
Felis catus GTF3C2 VGNC VGNC:67504
Macaca mulatta GTF3C2 VGNC VGNC:82153
Bos taurus GTF3C2 VGNC VGNC:29703
Rattus norvegicus GTF3C2 RGD RGD:1560392
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