2. Gene
  3. ZDHHC1 - zinc finger DHHC-type containing 1 Gene

ZDHHC1 - zinc finger DHHC-type containing 1 Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：含锌指 DHHC 型 1

种属: Homo sapiens

同用名: DHHC-1; ZNF377; C16orf1; HSU90653

基因 ID: 29800 | 基因类型: protein coding

关于 ZDHHC1

This gene has 6 transcripts (splice variants), 215 orthologues and 17 paralogues. Ubiquitous expression in ovary (RPKM 6.2), testis (RPKM 6.1) and 24 other tissues.

功能概要

启用棕榈酰转移酶活性。参与抗病毒先天免疫反应；宿主对病毒防御反应的正向调控；和蛋白质棕榈酰化。位于高尔基体和内质网膜。 [由基因组资源联盟提供，2022 年 4 月]

Enables palmitoyltransferase activity. Involved in Antiviral innate immune response; positive regulation of defense response to virus by host; and protein palmitoylation. Located in Golgi apparatus and endoplasmic reticulum membrane. [provided by Alliance of Genome Resources, Apr 2022]

ZDHHC1 基因产物(2)

mRNA Protein Name
NM_001323627.2 NP_001310556.1 palmitoyltransferase ZDHHC1 isoform 2
NM_013304.3 NP_037436.1 palmitoyltransferase ZDHHC1 isoform 1
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables palmitoyltransferase activity IDA
IDA: 通过直接分析推断
23034182 GOA
enables protein binding IPI
IPI: 通过物理相互作用推断
25299331 GOA
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in antiviral innate immune response IMP
IMP: 通过突变表型推断
25299331 GOA
involved in positive regulation of defense response to virus by host IMP
IMP: 通过突变表型推断
25299331 GOA
involved in protein palmitoylation IDA
IDA: 通过直接分析推断
23034182 GOA
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in Golgi apparatus IDA
IDA: 通过直接分析推断
25299331 GOA
located in endoplasmic reticulum IDA
IDA: 通过直接分析推断
16647879 GOA
located in endoplasmic reticulum membrane IDA
IDA: 通过直接分析推断
25299331 GOA
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

ZDHHC1 蛋白结构

DHHC

DHHC: DHHC palmitoyltransferase (112 - 283)

  • 0
  • 100
  • 200
  • 300
  • 400
  • 485 a.a.
蛋白主名 其他名称

palmitoyltransferase ZDHHC1

DHHC domain-containing cysteine-rich protein 1

ZDHHC1 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
Intra ZDHHC1 Q8WTX9 KRTAP10-8 Homo sapiens P60410
Y2H Array
32296183
Intra ZDHHC1 Q8WTX9 KRTAP10-8 Homo sapiens P60410
Y2H Prey Pooling
32296183
Intra ZDHHC1 Q8WTX9 KRTAP12-2 Homo sapiens P59991
Y2H Prey Pooling
32296183
Intra ZDHHC1 Q8WTX9 KRTAP12-2 Homo sapiens P59991
Y2H Array
32296183
Intra ZDHHC1 Q8WTX9 KRT83 Homo sapiens P78385
Y2H Array
32296183
Intra ZDHHC1 Q8WTX9 KRT83 Homo sapiens P78385
Y2H Prey Pooling
32296183
Intra ZDHHC1 Q8WTX9 KRTAP9-2 Homo sapiens Q9BYQ4
Validated Y2H
32296183
Intra ZDHHC1 Q8WTX9 KRTAP9-2 Homo sapiens Q9BYQ4
Y2H Array
32296183
Intra ZDHHC1 Q8WTX9 KRTAP9-2 Homo sapiens Q9BYQ4
Y2H Prey Pooling
32296183
Intra ZDHHC1 Q8WTX9 KRT34 Homo sapiens O76011
Y2H Prey Pooling
32296183
Intra ZDHHC1 Q8WTX9 KRT34 Homo sapiens O76011
Y2H Array
32296183
Intra ZDHHC1 Q8WTX9 GOPC Homo sapiens Q9HD26-2
Y2H Prey Pooling
32296183
Intra ZDHHC1 Q8WTX9 GOPC Homo sapiens Q9HD26-2
Validated Y2H
32296183
Intra ZDHHC1 Q8WTX9 GOPC Homo sapiens Q9HD26-2
Y2H Array
32296183
Intra ZDHHC1 Q8WTX9 KRTAP1-3 Homo sapiens Q8IUG1
Y2H Prey Pooling
32296183
Intra ZDHHC1 Q8WTX9 KRTAP1-3 Homo sapiens Q8IUG1
Y2H Array
32296183
Intra ZDHHC1 Q8WTX9 KRTAP12-3 Homo sapiens P60328
Y2H Prey Pooling
32296183
Intra ZDHHC1 Q8WTX9 KRTAP12-3 Homo sapiens P60328
Y2H Array
32296183
Intra ZDHHC1 Q8WTX9 KRTAP1-1 Homo sapiens Q07627
Y2H Prey Pooling
32296183
Intra ZDHHC1 Q8WTX9 KRTAP1-1 Homo sapiens Q07627
Y2H Array
32296183
Intra ZDHHC1 Q8WTX9 KRTAP17-1 Homo sapiens Q9BYP8
Y2H Prey Pooling
32296183
Intra ZDHHC1 Q8WTX9 KRTAP17-1 Homo sapiens Q9BYP8
Validated Y2H
32296183
Intra ZDHHC1 Q8WTX9 KRTAP17-1 Homo sapiens Q9BYP8
Y2H Array
32296183
Intra ZDHHC1 Q8WTX9 KRTAP2-4 Homo sapiens Q9BYR9
Y2H Array
32296183
Intra ZDHHC1 Q8WTX9 KRTAP2-4 Homo sapiens Q9BYR9
Y2H Prey Pooling
32296183
Intra ZDHHC1 Q8WTX9 KRTAP2-4 Homo sapiens Q9BYR9
Validated Y2H
32296183
Intra ZDHHC1 Q8WTX9 NOTCH2NLC Homo sapiens P0DPK4
Y2H Prey Pooling
32296183
Intra ZDHHC1 Q8WTX9 NOTCH2NLC Homo sapiens P0DPK4
Y2H Array
32296183
Intra ZDHHC1 Q8WTX9 CYSRT1 Homo sapiens A8MQ03
Y2H Prey Pooling
32296183
Intra ZDHHC1 Q8WTX9 CYSRT1 Homo sapiens A8MQ03
Y2H Array
32296183
Intra ZDHHC1 Q8WTX9 MDFI Homo sapiens Q99750
Y2H Prey Pooling
32296183
Intra ZDHHC1 Q8WTX9 MDFI Homo sapiens Q99750
Validated Y2H
32296183
Intra ZDHHC1 Q8WTX9 MDFI Homo sapiens Q99750
Y2H Array
32296183
Intra ZDHHC1 Q8WTX9 KRT31 Homo sapiens Q15323
Y2H Prey Pooling
32296183
Intra ZDHHC1 Q8WTX9 KRT31 Homo sapiens Q15323
Y2H Array
32296183
种属间: 跨种属相互作用 种属内: 同种属相互作用

关联疾病

疾病名称 别名
Immunodeficiency 10

Immune Dysfunction With T-Cell Inactivation Due To Calcium Entry Defect 2

Combined Immunodeficiency Due To Stim1 Deficiency

IMD10

Stim1 Deficiency

Cid Due To Stim1 Deficiency

Immune Dysfunction, With T-Cell Inactivation Due To Calcium Entry Defect 2

Immunodeficiency, Type 10
T Cell And Nk Cell Immunodeficiency
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS16011 ZDHHC1 Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Mus musculus ZDHHC1 MGD MGI:1918046
Canis familiaris ZDHHC1 VGNC VGNC:48577
Macaca mulatta ZDHHC1 VGNC VGNC:79102
Bos taurus ZDHHC1 VGNC VGNC:37126
Rattus norvegicus ZDHHC1 RGD RGD:1589775
Felis catus ZDHHC1 VGNC VGNC:67200
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