2. Gene
  3. Mink1 - misshapen-like kinase 1 Gene

Mink1 - misshapen-like kinase 1 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

中文名称：畸形样激酶 1

种属: Rattus norvegicus

同用名: MEKKK 6

基因 ID: 303259 | 基因类型: protein coding

关于 Mink1

Primary_assembly 10: 55,278,391-55,330,782 forward strand.mRatBN7.2:CM026983.1

This gene has 5 transcripts (splice variants), 204 orthologues, 36 paralogues and is associated with 2 phenotypes. Biased expression in Brain (RPKM 281.3), Kidney (RPKM 229.4) and 9 other tissues.

功能概要

预计该基因编码的蛋白可启动 ATP 结合活性和蛋白丝氨酸/苏氨酸激酶活性。涉及多个过程，包括树突形态发生；神经元细胞稳态；和 AMPA 受体活性的调节。预测位于高尔基体。预计在细胞质中有活性。与人类 MINK1 同源（畸形像激酶 1）。 [由基因组资源联盟提供，2022 年 4 月]

Predicted to enable ATP binding activity and protein serine/threonine kinase activity. Involved in several processes, including dendrite morphogenesis; neuron cellular homeostasis; and regulation of AMPA Receptor activity. Predicted to be located in Golgi apparatus. Predicted to be active in cytoplasm. Orthologous to human MINK1 (misshapen like kinase 1). [provided by Alliance of Genome Resources, Apr 2022]

Mink1 基因产物(3)

mRNA Protein Name
NM_001414353.1 NP_001401282.1 misshapen-like kinase 1 isoform 3
NM_001271136.2 NP_001258065.1 misshapen-like kinase 1 isoform 2
NM_001414352.1 NP_001401281.1 misshapen-like kinase 1 isoform 1

Mink1 蛋白结构

STKc_MAP4K4_6_N

STKc_MAP4K4_6_N: cd06636 (7 - 288)

PHA03307

PHA03307: cl33723 (548 - 844)

CNH

CNH: smart00036 (1065 - 1363)

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  • 1384 a.a.
蛋白主名 其他名称

misshapen-like kinase 1

GCK family kinase MiNK

MAPK/ERK kinase kinase kinase 6

MEK kinase kinase 6

misshapen/NIK-related kinase

mitogen-activated protein kinase kinase kinase kinase 6

相关产品

Approval
生物活性分子 (2)
目录号 产品名 作用方式
纯度 是否罕见病
HY-17437A Mefloquine hydrochloride 99.99% 是
HY-17437 Mefloquine / 否
Pre-clinical Phase
生物活性分子 (5)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-111754 DMX-5804 Inhibitor 99.83% 否
HY-108591 L-364,373 Activator 99.67% 否
HY-RS08454 MINK1 Human Pre-designed siRNA Set A Pre-designed Sets / 否
HY-RS08455 Mink1 Mouse Pre-designed siRNA Set A Pre-designed Sets / 否
HY-RS08456 Mink1 Rat Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Mink1 NCBI NCBI:50488
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