Tlr6 - toll-like receptor 6 Gene

中文名称：Toll 样受体 6

种属: Rattus norvegicus

关于 Tlr6

功能概要

该基因编码的蛋白可启动脂肽结合活性。参与几个过程，包括小胶质细胞激活；一氧化氮代谢过程；和对细菌脂蛋白的反应。预测位于高尔基体和膜筏。预计是 Toll 样受体 2-Toll 样受体 6 蛋白复合物的一部分。预计是质膜的组成部分。用于研究细菌性肺炎。围产期坏死性小肠结肠炎的生物标志物。该基因的人类直系同源物与曲霉病有关；哮喘;感染性心内膜炎;鼻炎;和肺结核。与人类 TLR6（toll 样受体 6）同源。 [由基因组资源联盟提供，2022 年 4 月]

Enables Lipopeptide binding activity. Involved in several processes, including microglial cell activation; nitric oxide metabolic process; and response to Bacterial lipoprotein. Predicted to be located in Golgi apparatus and membrane raft. Predicted to be part of Toll-like Receptor 2-Toll-like receptor 6 protein complex. Predicted to be integral component of plasma membrane. Used to study Bacterial pneumonia. Biomarker of perinatal necrotizing enterocolitis. Human ortholog(s) of this gene implicated in aspergillosis; asthma; infective endocarditis; rhinitis; and tuberculosis. Orthologous to human TLR6 (toll like receptor 6). [provided by Alliance of Genome Resources, Apr 2022]