2. Gene
  3. Ripk1 - receptor interacting serine/threonine kinase 1 Gene

Ripk1 - receptor interacting serine/threonine kinase 1 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

中文名称：受体相互作用 丝氨酸/苏氨酸激酶 1

种属: Rattus norvegicus

基因 ID: 306886 | 基因类型: protein coding

关于 Ripk1

Primary_assembly 17: 30,839,650-30,871,824 reverse strand.mRatBN7.2:CM026990.1

This gene has 1 transcript (splice variant), 198 orthologues, 23 paralogues and is associated with 5 phenotypes. Biased expression in Spleen (RPKM 117.7), Lung (RPKM 117.5) and 9 other tissues.

功能概要

该基因编码的蛋白可启动死亡受体结合活性。参与坏死过程的正调控。位于膜筏内。部分含蛋白质复合物。该基因与免疫缺陷 57 相关的人类直向同源基因。与人类 RIPK1（受体相互作用的丝氨酸/苏氨酸激酶 1）直向同源。 [由基因组资源联盟提供，2022 年 4 月]

Enables death receptor binding activity. Involved in positive regulation of necroptotic process. Located in membrane raft. Part of protein-containing complex. Human ortholog(s) of this gene implicated in immunodeficiency 57. Orthologous to human RIPK1 (receptor interacting serine/threonine kinase 1). [provided by Alliance of Genome Resources, Apr 2022]

Ripk1 基因产物(1)

mRNA Protein Name
NM_001107350.1 NP_001100820.1 receptor-interacting serine/threonine-protein kinase 1

Ripk1 蛋白结构

PKc_like

PKc_like: cl21453 (22 - 289)

Death_RIP1

Death_RIP1: cd08777 (569 - 654)

  • 0
  • 200
  • 400
  • 600
  • 658 a.a.
蛋白主名 其他名称

receptor-interacting serine/threonine-protein kinase 1

RIP

receptor (TNFRSF)-interacting serine-threonine kinase 1

相关产品

Clinical Phase
生物活性分子 (1)
目录号 产品名 作用方式
纯度 Phase
HY-148787 Oditrasertib Inhibitor 99.24% Phase 2
Pre-clinical Phase
生物活性分子 (26)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-14622A Necrostatin 2 racemate Inhibitor 99.65% 否
HY-134050 Apostatin-1 Inhibitor 99.84% 否
HY-138779 ICCB-19 hydrochloride Inhibitor 99.24% 否
HY-14622 Necrostatin 2 Inhibitor 99.92% 否
HY-114492 GSK547 Inhibitor 99.92% 否
HY-114371 Eclitasertib Inhibitor 99.77% 否
HY-128348 PK68 Inhibitor 99.92% 否
HY-124546 Necrostatin-5 Inhibitor 98.43% 否
HY-132203 Necrostatin-34 Inhibitor 98.90% 否
HY-148365 NecroIr1 Activator 98.02% 否
HY-149258 KWCN-41 Inhibitor 99.83% 否
HY-148297 Ocadusertib Inhibitor 98.75% 否
HY-148366 NecroIr2 Activator 98.99% 否
HY-151873 SZM679 Inhibitor 99.59% 否
HY-153434 RIP1 kinase inhibitor 4 Inhibitor / 否
HY-149052 SZM-1209 Inhibitor / 否
HY-162237 RIPK1-IN-22 Inhibitor / 否
HY-161911 Necroptosis-IN-5 Inhibitor / 否
HY-158334 NDs-IN-1 Inhibitor / 否
HY-157456 RIPK1-IN-19 Inhibitor ≥98.0% 否
HY-146758 RIPK1-IN-14 Inhibitor / 否
HY-157963 RIPK1-IN-23 Inhibitor / 否
HY-18899 Nec-3a Inhibitor / 否
HY-160216 RIPK1-IN-18 Inhibitor / 否
HY-153437 RIP1 kinase inhibitor 7 Inhibitor / 否
HY-169107 RIPK1-IN-25 Inhibitor / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Ripk1 NCBI NCBI:8737
Canis familiaris Ripk1 NCBI NCBI:102152063
Macaca fascicularis Ripk1 NCBI NCBI:101926590
Canis lupus familiaris Ripk1 NCBI
Mus musculus Ripk1 NCBI NCBI:19766
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