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  2. Gpr4 - G protein-coupled receptor 4 Gene

Gpr4 - G protein-coupled receptor 4 Gene

中文名称:G 蛋白偶联受体 4

种属: Rattus norvegicus

基因 ID: 308408 | 基因类型: protein coding

关于 Gpr4

Primary_assembly 1: 78,865,409-78,876,599 forward strand.mRatBN7.2:CM026974.1

This gene has 1 transcript (splice variant), 141 orthologues and 14 paralogues. Biased expression in Heart (RPKM 15.7), Lung (RPKM 12.4) and 9 other tissues.

功能概要

预计该基因编码的蛋白可启动 G 蛋白偶联受体活性。预计参与多个过程,包括G蛋白偶联受体信号通路; Rho 蛋白信号转导的正调控;和对酸性 pH 值的反应。预计作用于 G 蛋白偶联受体信号通路的上游或内部;血管发育;和血管生成的负调节。预测位于质膜中。预计是质膜的组成部分。与人类 GPR4(G 蛋白偶联受体 4)同源。 [由基因组资源联盟提供,2022 年 4 月]

Predicted to enable G protein-coupled receptor activity. Predicted to be involved in several processes, including G protein-coupled receptor signaling pathway; positive regulation of Rho protein signal transduction; and response to acidic pH. Predicted to act upstream of or within G protein-coupled receptor signaling pathway; blood vessel development; and negative regulation of angiogenesis. Predicted to be located in plasma membrane. Predicted to be integral component of plasma membrane. Orthologous to human GPR4 (G protein-coupled receptor 4). [provided by Alliance of Genome Resources, Apr 2022]

Gpr4 基因产物(1)

mRNA Protein Name
NM_001025680.1 NP_001020851.1 G-protein coupled receptor 4

Gpr4 蛋白结构

7tmA_GPR4

7tmA_GPR4: cd15366 (19 - 46)

7tmA_GPR4

7tmA_GPR4: cd15366 (19 - 298)

7tmA_GPR4

7tmA_GPR4: cd15366 (53 - 78)

7tmA_GPR4

7tmA_GPR4: cd15366 (91 - 121)

7tmA_GPR4

7tmA_GPR4: cd15366 (133 - 155)

7tmA_GPR4

7tmA_GPR4: cd15366 (179 - 208)

7tmA_GPR4

7tmA_GPR4: cd15366 (218 - 248)

7tmA_GPR4

7tmA_GPR4: cd15366 (266 - 291)

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  • 365 a.a.
蛋白主名 其他名称

G-protein coupled receptor 4

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Gpr4 NCBI NCBI:2828