2. Gene
  3. Wee1 - WEE1 G2 checkpoint kinase Gene

Wee1 - WEE1 G2 checkpoint kinase Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

中文名称：WEE1 G2 检查点激酶

种属: Rattus norvegicus

基因 ID: 308937 | 基因类型: protein coding

关于 Wee1

Primary_assembly 1: 164,174,779-164,197,688 forward strand.mRatBN7.2:CM026974.1

This gene has 2 transcripts (splice variants), 227 orthologues, 8 paralogues and is associated with 1 phenotype. Biased expression in Testes (RPKM 65.2), Thymus (RPKM 58.) and 9 other tissues.

功能概要

预测该基因编码的蛋白编码的蛋白可启动蛋白酪氨酸激酶活性。预测参与细胞分裂和有丝分裂细胞周期。预计在几个过程的上游或内部起作用，包括建立细胞极性；神经元投射形态发生；和肽基酪氨酸磷酸化。预测位于细胞质和核仁中。预计活跃于核心。与人类 WEE1（WEE1 G2 检查点激酶）同源。 [由基因组资源联盟提供，2022 年 4 月]

Predicted to enable protein tyrosine kinase activity. Predicted to be involved in cell division and mitotic cell cycle. Predicted to act upstream of or within several processes, including establishment of cell polarity; neuron projection morphogenesis; and peptidyl-tyrosine phosphorylation. Predicted to be located in cytoplasm and nucleolus. Predicted to be active in nucleus. Orthologous to human Wee1 (Wee1 G2 checkpoint kinase). [provided by Alliance of Genome Resources, Apr 2022]

Wee1 基因产物(1)

mRNA Protein Name
NM_001012742.1 NP_001012760.1 wee1-like protein kinase

Wee1 蛋白结构

PTKc_Wee1a

PTKc_Wee1a: cd14138 (291 - 566)

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  • 646 a.a.
蛋白主名 其他名称

wee1-like protein kinase

wee 1 homolog

wee1 tyrosine kinase

wee1A kinase

相关产品

Approval
生物活性分子 (1)
目录号 产品名 作用方式
纯度 是否罕见病
HY-17583 Griseofulvin 99.05% 否
Clinical Phase
生物活性分子 (2)
目录号 产品名 作用方式
纯度 Phase
HY-10993 Adavosertib Inhibitor 99.97% Phase 2
HY-145817A lunresertib Inhibitor 99.97% Phase 2
Pre-clinical Phase
生物活性分子 (38)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-132295 Azenosertib Inhibitor 99.96% 否
HY-13925 PD0166285 Inhibitor 99.46% 否
HY-18961 PD 407824 Inhibitor 99.00% 否
HY-147054 WEE1-IN-5 Inhibitor 99.46% 否
HY-147312 GSK-1520489A Inhibitor 98.33% 否
HY-122113 PD173952 Inhibitor 99.44% 否
HY-148062 RSS0680 98.03% 否
HY-133618 Pomalidomide-C3-adavosertib Degrader 99.84% 否
HY-12400 GSK3182571 Inhibitor 99.75% 否
HY-108343 WEE1-IN-4 Inhibitor 99.60% 否
HY-145817 (Rac)-lunresertib Inhibitor 99.72% 否
HY-145664 Myt1-IN-1 Inhibitor 98.97% 否
HY-145817B (R)-lunresertib Inhibitor 99.87% 否
HY-138239 WEE1-IN-3 Inhibitor 98.64% 否
HY-144999 LEB-03-146 98.08% 否
HY-103029 Bosutinib isomer Inhibitor 99.62% 否
HY-145666 Myt1-IN-3 Inhibitor 99.14% 否
HY-170517 PKMYT1-IN-8 Inhibitor / 否
HY-163490 PKMYT1-IN-1 Inhibitor / 否
HY-145665 Myt1-IN-2 Inhibitor / 否
HY-163491 PKMYT1-IN-2 Inhibitor / 否
HY-157443 Myt1-IN-4 Inhibitor / 否
HY-143340 LEB-03-145 / 否
HY-160530 WEE1-IN-6 Inhibitor / 否
HY-161871 WEE1-IN-8 Inhibitor / 否
HY-13925A PD0166285 dihydrochloride Inhibitor / 否
HY-163697 WEE1-IN-7 Inhibitor / 否
HY-162849 PKMYT1-IN-3 Inhibitor / 否
HY-161879 WEE1-IN-9 Inhibitor / 否
HY-143343 LEB-03-153 / 否
HY-169946 WEE1/PKMYT1-IN-1 Inhibitor / 否
HY-168180 WEE1-IN-11 Inhibitor / 否
HY-143342 LEB-03-144 / 否
HY-168654 WEE1 degrader 1 Degrader / 否
HY-161880 WEE1-IN-10 Inhibitor / 否
HY-162986 PKMYT1-IN-4 Inhibitor / 否
HY-162988 Myt1-IN-5 Inhibitor / 否
HY-162987 PKMYT1-IN-6 Inhibitor / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Wee1 NCBI NCBI:7465
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