Nfkb2 - nuclear factor kappa B subunit 2 Gene

中文名称：核因子 κB 亚基 2

种属: Rattus norvegicus

同用名: RGD1307189

关于 Nfkb2

功能概要

预测该基因编码的蛋白可实现 DNA 结合转录激活因子活性、RNA 聚合酶 II 特异性和 RNA 聚合酶 II 顺式调节区序列特异性 DNA 结合活性。参与衰老；对细胞因子的反应；和对脂多糖的反应。位于细胞质和细胞核中。用于研究帕金森症。该基因的人类直系同源物与常见的可变免疫缺陷有关。与人类 NFKB2（核因子 kappa B 亚基 2）同源。 [由基因组资源联盟提供，2022 年 4 月]

Predicted to enable DNA-binding transcription activator activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in aging; response to cytokine; and response to lipopolysaccharide. Located in cytosol and nucleus. Used to study Parkinsonism. Human ortholog(s) of this gene implicated in common variable immunodeficiency. Orthologous to human NFKB2 (nuclear factor kappa B subunit 2). [provided by Alliance of Genome Resources, Apr 2022]