2. Gene
  3. Epha4 - Eph receptor A4 Gene

Epha4 - Eph receptor A4 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Rattus norvegicus

同用名: RGD1560587

基因 ID: 316539 | 基因类型: protein coding

关于 Epha4

功能概要

Enables Ephrin Receptor binding activity. Involved in several processes, including regulation of modification of synaptic structure; regulation of neuron projection development; and synapse pruning. Located in several cellular components, including dendrite; distal axon; and perikaryon. Is integral component of plasma membrane. Is active in glutamatergic synapse. Biomarker of toxic encephalopathy. Orthologous to human EphA4 (EPH receptor A4). [provided by Alliance of Genome Resources, Apr 2022]

Epha4 基因产物(1)

mRNA Protein Name
NM_001162411.1 NP_001155883.1 ephrin type-A receptor 4 precursor
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables ephrin receptor binding IDA
IDA: 通过直接分析推断
10366629 RGD
enables protein binding IPI
IPI: 通过物理相互作用推断
12775584 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in glial cell migration IMP
IMP: 通过突变表型推断
20335460 RGD
NOT involved in negative regulation of axon regeneration IMP
IMP: 通过突变表型推断
17418490 RGD
involved in negative regulation of axon regeneration IMP
IMP: 通过突变表型推断
17970742 RGD
involved in positive regulation of dendrite morphogenesis IMP
IMP: 通过突变表型推断
19414612 RGD
involved in regulation of modification of synaptic structure IGI
IGI: 通过遗传相互作用推断
24658113 RGD
involved in regulation of synapse pruning EXP
EXP: 通过实验结果推断
17143272 RGD
involved in regulation of synapse pruning IDA
IDA: 通过直接分析推断
17143272 RGD
involved in regulation of synapse pruning IEP
IEP: 通过表达模式推断
17143272 RGD
involved in regulation of synapse pruning IMP
IMP: 通过突变表型推断
17143272 RGD
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in axon terminus IDA
IDA: 通过直接分析推断
19086003 RGD
located in axonal growth cone IDA
IDA: 通过直接分析推断
19086003 RGD
located in cell body IDA
IDA: 通过直接分析推断
19086003 RGD
located in cell projection IDA
IDA: 通过直接分析推断
19086003 RGD
located in cell surface IDA
IDA: 通过直接分析推断
19086003 RGD
located in cytoplasm IDA
IDA: 通过直接分析推断
12775584 RGD
located in dendrite IDA
IDA: 通过直接分析推断
19086003 RGD
located in dendritic shaft IDA
IDA: 通过直接分析推断
24658113 RGD
located in dendritic spine IDA
IDA: 通过直接分析推断
19086003 RGD
located in filopodium IDA
IDA: 通过直接分析推断
19086003 RGD
is active in glutamatergic synapse EXP
EXP: 通过实验结果推断
17143272 RGD
is active in glutamatergic synapse IDA
IDA: 通过直接分析推断
17143272 RGD
is active in glutamatergic synapse IMP
IMP: 通过突变表型推断
17143272 RGD
located in mitochondrial outer membrane IDA
IDA: 通过直接分析推断
19086003 RGD
located in neuromuscular junction IDA
IDA: 通过直接分析推断
11414792 RGD
located in perikaryon IDA
IDA: 通过直接分析推断
19086003 RGD
located in plasma membrane IDA
IDA: 通过直接分析推断
17143272 RGD
located in postsynaptic density IDA
IDA: 通过直接分析推断
17143272 RGD
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

ephrin type-A receptor 4

重组 Epha4 蛋白

目录号 产品名 蛋白编号 纯度
HY-P75238 EphA4 Protein, Rat (HEK293, His) D3ZZK3 (V20-T547) ≥95%
HY-P75239 EphA4 Protein, Rat (HEK293, Fc) D3ZZK3 (V20-T547) ≥95%

相关产品

Pre-clinical Phase
生物活性分子 (2)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-159174 EPHA2/A4/GAK-IN-1 Inhibitor / 否
HY-171175 UniPR500 Antagonist / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Epha4 NCBI NCBI:2043
Mus musculus Epha4 NCBI NCBI:13838
Macaca mulatta Epha4 NCBI NCBI:704857
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