2. Gene
  3. Sctr - secretin receptor Gene

Sctr - secretin receptor Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

中文名称：分泌素受体

种属: Mus musculus

同用名: 6530402O03Rik

基因 ID: 319229 | 基因类型: protein coding

关于 Sctr

Chromosome 1: 119,934,624-119,991,266 forward strand.GRCm39:CM000994.3

This gene has 2 transcripts (splice variants), 130 orthologues, 41 paralogues and is associated with 30 phenotypes. Biased expression in stomach adult (RPKM 11.4), adrenal adult (RPKM 3.1) and 3 other tissues.

功能概要

该基因编码的蛋白可启动胰泌素受体活性。涉及多个过程，包括饮食诱导的产热；正向调节 cAMP 介导的信号；和水稳态。预测位于细胞质微管中。预计在质膜上有活性。与人类 SCTR（分泌素受体）同源。 [由基因组资源联盟提供，2022 年 4 月]

Enables Secretin Receptor activity. Involved in several processes, including diet induced thermogenesis; positive regulation of cAMP-mediated signaling; and water homeostasis. Predicted to be located in cytoplasmic microtubule. Predicted to be active in plasma membrane. Orthologous to human SCTR (Secretin Receptor). [provided by Alliance of Genome Resources, Apr 2022]

Sctr 基因产物(2)

mRNA Protein Name
NM_001311077.1 NP_001298006.1 secretin receptor isoform 2 precursor
NM_001012322.2 NP_001012322.2 secretin receptor isoform 1 precursor
基因本体论
  • 分子功能
  • 生物过程
分子功能 GO 注释 逻辑证据 参考文献 来源
enables secretin receptor activity IDA
IDA: 通过直接分析推断
30449620 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in adenylate cyclase-activating G protein-coupled receptor signaling pathway IDA
IDA: 通过直接分析推断
30449620 MGI
involved in diet induced thermogenesis IDA
IDA: 通过直接分析推断
30449620 MGI
involved in intracellular water homeostasis IMP
IMP: 通过突变表型推断
17283064 MGI
involved in positive regulation of lipid catabolic process IDA
IDA: 通过直接分析推断
30449620 MGI
involved in positive regulation of lipid catabolic process IMP
IMP: 通过突变表型推断
24273196 MGI
involved in regulation of appetite IDA
IDA: 通过直接分析推断
30449620 MGI
involved in regulation of appetite IMP
IMP: 通过突变表型推断
20927047 MGI
involved in regulation of synaptic plasticity IMP
IMP: 通过突变表型推断
17008357 MGI
involved in renal water absorption IMP
IMP: 通过突变表型推断
17283064 MGI
involved in response to nutrient levels IDA
IDA: 通过直接分析推断
30449620 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

Sctr 蛋白结构

HRM

HRM: pfam02793 (76 - 139)

7tmB1_secretin

7tmB1_secretin: cd15275 (152 - 418)

7tmB1_secretin

7tmB1_secretin: cd15275 (154 - 179)

7tmB1_secretin

7tmB1_secretin: cd15275 (188 - 210)

7tmB1_secretin

7tmB1_secretin: cd15275 (229 - 256)

7tmB1_secretin

7tmB1_secretin: cd15275 (268 - 288)

7tmB1_secretin

7tmB1_secretin: cd15275 (304 - 333)

7tmB1_secretin

7tmB1_secretin: cd15275 (349 - 376)

7tmB1_secretin

7tmB1_secretin: cd15275 (380 - 405)

  • 0
  • 100
  • 200
  • 300
  • 400
  • 464 a.a.
蛋白主名 其他名称

secretin receptor

SCT-R

相关产品

Pre-clinical Phase
生物活性分子 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS12568 SCTR Human Pre-designed siRNA Set A Pre-designed Sets / 否
HY-RS12569 Sctr Mouse Pre-designed siRNA Set A Pre-designed Sets / 否
HY-RS12570 Sctr Rat Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Sctr NCBI NCBI:6344
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