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  2. HSPA9 - heat shock protein family A (Hsp70) member 9 Gene

HSPA9 - heat shock protein family A (Hsp70) member 9 Gene

中文名称:热休克蛋白家族 A (Hsp70) 成员 9

种属: Homo sapiens

同用名: CSA; MOT; MOT2; SAAN; CRP40; EVPLS; GRP75; PBP74; GRP-75; HSPA9B; SIDBA4; MTHSP75; HEL-S-124m

基因 ID: 3313 | 基因类型: protein coding

关于 HSPA9

Cytogenetic location: 5q31.2 Genomic coordinates (GRCh38): 5:138,553,756-138,575,401 (from NCBI)

This gene has 23 transcripts (splice variants), 234 orthologues, 13 paralogues and is associated with 4 phenotypes. Ubiquitous expression in adrenal (RPKM 109.2), thyroid (RPKM 92.6) and 25 other tissues.

功能概要

该基因编码热休克蛋白 70 基因家族的成员。编码的蛋白质主要定位于线粒体,但也存在于内质网、质膜和细胞质囊泡中。这种蛋白质是一种热休克同源蛋白质。这种蛋白质在细胞增殖、应激反应和线粒体维持中发挥作用。在 2 号染色体上发现了该基因的假基因。[RefSeq 提供,2010 年 5 月]

This gene encodes a member of the heat shock protein 70 gene family. The encoded protein is primarily localized to the mitochondria but is also found in the endoplasmic reticulum, plasma membrane and cytoplasmic vesicles. This protein is a heat-shock cognate protein. This protein plays a role in cell proliferation, stress response and maintenance of the mitochondria. A pseudogene of this gene is found on chromosome 2.[provided by RefSeq, May 2010]

HSPA9 基因产物(1)

mRNA Protein Name
NM_004134.7 NP_004125.3 stress-70 protein, mitochondrial precursor

HSPA9 蛋白结构

HSP70

HSP70: Hsp70 protein (55 - 652)

  • 0
  • 200
  • 400
  • 600
  • 679 a.a.
蛋白主名 其他名称

stress-70 protein, mitochondrial

75 kDa glucose-regulated protein

HSPA9 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
种属内
HSPA9 P38646 YKT6 Homo sapiens A4D2J0 25416956
种属内
HSPA9 P38646 YKT6 Homo sapiens A4D2J0 25416956
种属内
HSPA9 P38646 GRPEL1 Homo sapiens Q9HAV7 23263864
种属内
HSPA9 P38646 HSCB Homo sapiens Q8IWL3 24606901
种属内
HSPA9 P38646 GPBAR1 Homo sapiens Q8TDU6 31978385
种属内
HSPA9 P38646 GPBAR1 Homo sapiens Q8TDU6
IF
31978385
种属内
HSPA9 P38646 EGFR Homo sapiens P00533 20029029
种属内
HSPA9 P38646 NELFB Homo sapiens Q8WX92 20195357
种属内
HSPA9 P38646 NELFB Homo sapiens Q8WX92
TAP
20195357
种属内
HSPA9 P38646 TP73 Homo sapiens O15350
IF
22340593
种属间: 跨种属相互作用 种属内: 同种属相互作用

HSPA9 抗体

目录号 产品名 应用 反应物种
HY-P83410 GRP75 Antibody (YA3155) WB Human, Mouse, Rat

关联疾病

疾病名称 别名
Even-Plus Syndrome

EVPLS

Epiphyseal And Vertebral Dysplasia, Microtia, And Flat Nose, Plus Associated Malformations

Epiphysial-Vertebral-Ear Dysplasia-Nose-Plus Associated Findings Syndrome

Anemia, Sideroblastic, 4

SIDBA4

Anemia, Sideroblastic, Type 4

Autosomal Recessive Sideroblastic Anemia

Arsa

Congenital Sideroblastic Anemia

Hereditary Sideroblastic Anemia

Sideroblastic Anemia

Anemia Sideroblastic

Anemia, Sideroblastic

Anemia, Hypochromic With Iron Loading

Friedreich Ataxia

Friedreich Ataxia 1

FRDA

Friedreich Ataxia With Retained Reflexes

Frda1

Fa

Friedreich'S Ataxia

Hereditary Spinal Ataxia

Fa1

Friedreich'S Tabes

Hereditary Spinal Sclerosis

Spinocerebellar Ataxia, Friedreich

Friedreich Spinocerebellar Ataxia

Friedrich'S Ataxia

Codas Syndrome

Cerebral, Ocular, Dental, Auricular, And Skeletal Anomalies Syndrome

Cerebral, Ocular, Dental, Auricular, And Skeletal Syndrome

Cerebro-Oculo-Dento-Auriculo-Skeletal Syndrome

Cerebrooculodentoauriculoskeletal Syndrome

CODASS

Cerebral, Ocular, Dental, Auricular, Skeletal Syndrome

Leukodystrophy, Hypomyelinating, 4

Mitochondrial Hsp60 Chaperonopathy

Hypomyelinating Leukodystrophy 4

HLD4

Mitchap60 Disease

Pelizaeus-Merzbacher-Like Disease Due To Hspd1 Mutation

Mitchap-60 Disease

Leukodystrophy, Hypomyelinating, Type 4

Complement Component 7 Deficiency

C7 Deficiency

C7D

Parkinson Disease, Late-Onset

Parkinson Disease

Parkinson'S Disease

PD

PARK

Parkinson Disease, Susceptibility To

Late Onset Parkinson'S Disease

Late Onset Parkinson Disease

Paralysis Agitans

Primary Parkinsonism

Idiopathic Parkinson Disease

Parkinson'S

Parkinson Disease, Late-Onset, Susceptibility To

Parkinson Disease, Age Of Onset, Modifier

Lewy Body Parkinson Disease

Idiopathic Parkinson'S Disease

Pd - [Parkinson Disease]

Parkinson Disease Nos

Parkinson, Nos

Primary Parkinson Disease

Perrault Syndrome

Gonadal Dysgenesis, Xx Type, With Deafness

Ovarian Dysgenesis With Sensorineural Deafness

Gonadal Dysgenesis, Xx Type

Gonadal Dysgenesis With Auditory Dysfunction, Autosomal Recessive Inheritance

Gonadal Dysgenesis With Sensorineural Deafness, Autosomal Recessive Inheritance

Xx Gonodal Dysgenesis-Deafness Syndrome

Xx Gonodal Dysgenesis-Hearing Loss Syndrome

Gonadal Dysgenesis Xx Type Deafness

Hereditary Spastic Paraplegia

Familial Spastic Paraplegia

Hereditary Spastic Paraparesis

Strumpell-Lorrain Disease

Familial Spastic Paraparesis

Hsp

Spg

Strümpell-Lorrain Disease

Spastic Paraplegia, Hereditary

French Settlement Disease

Strumpell-Lorrain Syndrome

Fsp

Spastic Paraplegia, Familial

Spastic Paraplegia Hereditary

Spastic Paraplegia 3, Autosomal Dominant

Spastic Paraparesis

Hereditary Spastic Paralysis

Familial Spastic Paralysis

Hereditary Spastic Ataxia

疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

直系同源

种属 基因名 来源 基因 ID
Bos taurus HSPA9 VGNC VGNC:52243
Mus musculus HSPA9 MGD MGI:96245
Macaca mulatta HSPA9 VGNC VGNC:84389
Felis catus HSPA9 VGNC VGNC:102228
Rattus norvegicus HSPA9 RGD RGD:1311806
Canis familiaris HSPA9 VGNC VGNC:51725
Others HSPA9 NCBI