2. Gene
  3. EZHIP - EZH inhibitory protein Gene

EZHIP - EZH inhibitory protein Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：EZH 抑制蛋白

种属: Homo sapiens

同用名: KIP75; CXorf67; CATACOMB

基因 ID: 340602 | 基因类型: protein coding

关于 EZHIP

Cytogenetic location: Xp11.22 Genomic coordinates (GRCh38): X:51,406,948-51,408,843 (from NCBI)

This gene has 1 transcript (splice variant) and 64 orthologues.

功能概要

参与组蛋白 H3-K27 甲基化的负调控。位于细胞质和核质中。 [由基因组资源联盟提供，2022 年 4 月]

Involved in negative regulation of histone H3-K27 methylation. Located in cytosol and nucleoplasm. [provided by Alliance of Genome Resources, Apr 2022]

EZHIP 基因产物(1)

mRNA Protein Name
NM_203407.3 NP_981952.1 EZH inhibitory protein
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables histone methyltransferase inhibitor activity IDA
IDA: 通过直接分析推断
30923826 GOA
enables protein binding IPI
IPI: 通过物理相互作用推断
29909548 GOA
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in chromatin organization IDA
IDA: 通过直接分析推断
29909548 GOA
involved in epigenetic regulation of gene expression IDA
IDA: 通过直接分析推断
30923826 GOA
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in cytosol IDA
IDA: 通过直接分析推断
30923826 GOA
located in nucleus IDA
IDA: 通过直接分析推断
29909548 GOA
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

EZH inhibitory protein

K27M-like inhibitor of PRC2

EZHIP 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
Intra EZHIP Q86X51 TRAF4 Homo sapiens Q9BUZ4
Validated Y2H
32296183
Intra EZHIP Q86X51 TRIM41 Homo sapiens Q8WV44
Validated Y2H
32296183
Intra EZHIP Q86X51 ZNF417 Homo sapiens Q8TAU3
Validated Y2H
32296183
Intra EZHIP Q86X51 ENKD1 Homo sapiens Q9H0I2
Validated Y2H
32296183
Intra EZHIP Q86X51 SCNM1 Homo sapiens Q9BWG6
Validated Y2H
32296183
种属间: 跨种属相互作用 种属内: 同种属相互作用

关联疾病

疾病名称 别名
Posterior Fossa Ependymoma
Myxoid Leiomyosarcoma

Leiomyosarcoma, Myxoid
Central Nervous System Germ Cell Tumor

Central Nervous System Germ Cell Tumour

Germ Cell Tumor Of The Cns

Germ Cell Tumour Of The Cns
High Grade Ependymoma

Ependymal Neoplasm

Ependymal Tumors

Malignant Ependymoma

Ependymal Tumor

Anaplastic Ependymoma

Experimental Organism Malignant Ependymoma

Ependymoma Of Brain
Endometrial Stromal Nodule
Endometrial Stromal Tumor

Endometrial Stromal Neoplasm

Endometrial Stromal Tumors
Cerebral Ventricle Cancer

Cerebral Ventricle Neoplasms

Cerebral Ventricle Neoplasm

Intraventricular Tumor Of Brain
Supratentorial Ependymoma
Cerebrum Cancer

Cerebral Cancer

Neoplasm Of Cerebrum

Tumor Of Cerebrum

Malignant Neoplasm Of Cerebrum
Supratentorial Cancer

Supratentorial Neoplasms

Brain Neoplasm, Supratentorial

Malignant Supratentorial Tumor

Cancer, Supratentorial
Endometrial Stromal Sarcoma

Ess

Endometrial Stromal Sarcoma, High Grade

Undifferentiated Endometrial Sarcoma

Stromal Sarcoma Of The Corpus Uteri

Sarcoma Endometrial Stromal

Sarcoma, Endometrial Stromal

Undifferentiated Stromal Sarcoma
Cns Neuroblastoma With Foxr2 Activation

Central Nervous System Neuroblastoma With Foxr2 Activation

Cns Nb-Foxr2

Cns Neuroblastoma, Foxr2-Activated
Central Nervous System Neuroblastoma
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS04622 EZHIP Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Rattus norvegicus EZHIP RGD RGD:7681336
Mus musculus EZHIP MGD MGI:2147968
Macaca mulatta EZHIP VGNC VGNC:108075
Bos taurus EZHIP VGNC VGNC:108084
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