1. Gene
  2. ARPIN - actin related protein 2/3 complex inhibitor Gene

ARPIN - actin related protein 2/3 complex inhibitor Gene

中文名称:肌动蛋白相关蛋白 2/3 复合物抑制因子

种属: Homo sapiens

同用名: C15orf38

基因 ID: 348110 | 基因类型: protein coding

关于 ARPIN

Cytogenetic location: 15q26.1 Genomic coordinates (GRCh38): 15:89,895,006-89,912,952 (from NCBI)

This gene has 3 transcripts (splice variants) and 177 orthologues. Ubiquitous expression in colon (RPKM 5.0), ovary (RPKM 4.4) and 24 other tissues.

功能概要

参与定向运动;细胞迁移的负调节;和细胞成分组织的负调节。预计位于 lamellipodium。 [由基因组资源联盟提供,2022 年 4 月]

Involved in directional locomotion; negative regulation of cell migration; and negative regulation of cellular component organization. Predicted to be located in lamellipodium. [provided by Alliance of Genome Resources, Apr 2022]

ARPIN 基因产物(2)

mRNA Protein Name
NM_001282380.2 NP_001269309.1 arpin isoform 2
NM_182616.4 NP_872422.1 arpin isoform 1

ARPIN 蛋白结构

UPF0552

UPF0552: Uncharacterised protein family UPF0552 (1 - 224)

  • 0
  • 100
  • 200
  • 226 a.a.
蛋白主名 其他名称

arpin

UPF0552 protein C15orf38

ARPIN 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
Intra ARPIN Q7Z6K5 NIF3L1 Homo sapiens Q9GZT8
Y2H Prey Pooling
25416956
Intra ARPIN Q7Z6K5 DDIT4L Homo sapiens Q96D03
Y2H Array
32296183
Intra ARPIN Q7Z6K5 DDIT4L Homo sapiens Q96D03
Y2H Prey Pooling
32296183
Intra ARPIN Q7Z6K5 DDIT4L Homo sapiens Q96D03
Validated Y2H
32296183
种属间: 跨种属相互作用 种属内: 同种属相互作用

关联疾病

疾病名称 别名
Emery-Dreifuss Muscular Dystrophy 4, Autosomal Dominant

EDMD4

Emery-Dreifuss Muscular Dystrophy 4 With Variable Features

Autosomal Dominant Emery-Dreifuss Muscular Dystrophy 4

Emd4

Dystrophy, Muscular, Emery-Dreifuss, Type 4, Autosomal Dominant

Emery-Dreifuss Muscular Dystrophy 4

疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

直系同源

种属 基因名 来源 基因 ID
Rattus norvegicus ARPIN RGD RGD:1311021
Mus musculus ARPIN MGD MGI:1917670
Canis familiaris ARPIN VGNC VGNC:108041
Bos taurus ARPIN VGNC VGNC:108040
Others ARPIN NCBI