1. Gene
  2. GPR141 - G protein-coupled receptor 141 Gene

GPR141 - G protein-coupled receptor 141 Gene

中文名称:G 蛋白偶联受体 141

种属: Homo sapiens

同用名: PGR13

基因 ID: 353345 | 基因类型: protein coding

关于 GPR141

Cytogenetic location: 7p14.1 Genomic coordinates (GRCh38): 7:37,683,766-37,743,835 (from NCBI)

This gene has 5 transcripts (splice variants), 195 orthologues and 7 paralogues. Biased expression in bone marrow (RPKM 2.2), appendix (RPKM 0.5) and 10 other tissues.

功能概要

GPR141 是 G 蛋白偶联受体 (GPR) 视紫红质家族的成员 (Fredriksson 等人,2003 [PubMed 14623098]) 。[OMIM 提供,2008 年 3 月]

GPR141 is a member of the rhodopsin family of G protein-coupled receptors (GPRs) (Fredriksson et al., 2003 [PubMed 14623098]).[supplied by OMIM, Mar 2008]

GPR141 基因产物(4)

mRNA Protein Name
NM_001329993.2 NP_001316922.1 probable G-protein coupled receptor 141
NM_001329994.2 NP_001316923.1 probable G-protein coupled receptor 141
NM_001381946.1 NP_001368875.1 probable G-protein coupled receptor 141
NM_181791.3 NP_861456.1 probable G-protein coupled receptor 141
基因本体论
  • 分子功能
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
32814053 GOA
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断

GPR141 蛋白结构

7tm_1

7tm_1: 7 transmembrane receptor (rhodopsin family) (38 - 259)

  • 0
  • 100
  • 200
  • 305 a.a.
蛋白主名 其他名称

probable G-protein coupled receptor 141

G-protein coupled receptor PGR13

GPR141 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
种属内
GPR141 Q7Z602 KIF1B Homo sapiens O60333-2 32814053
种属内
GPR141 Q7Z602 KIF1B Homo sapiens O60333-2 32814053
种属内
GPR141 Q7Z602 KIF1B Homo sapiens O60333-2 32814053
种属内
GPR141 Q7Z602 DMWD Homo sapiens G5E9A7 32814053
种属内
GPR141 Q7Z602 DMWD Homo sapiens G5E9A7 32814053
种属内
GPR141 Q7Z602 DMWD Homo sapiens G5E9A7 32814053
种属内
GPR141 Q7Z602 CTSD Homo sapiens P07339 32814053
种属内
GPR141 Q7Z602 CTSD Homo sapiens P07339 32814053
种属内
GPR141 Q7Z602 CTSD Homo sapiens P07339 32814053
种属内
GPR141 Q7Z602 HSPB1 Homo sapiens P04792 32814053
种属内
GPR141 Q7Z602 HSPB1 Homo sapiens P04792 32814053
种属内
GPR141 Q7Z602 HSPB1 Homo sapiens P04792 32814053
种属内
GPR141 Q7Z602 RNF11 Homo sapiens Q9Y3C5 32814053
种属内
GPR141 Q7Z602 RNF11 Homo sapiens Q9Y3C5 32814053
种属内
GPR141 Q7Z602 RNF11 Homo sapiens Q9Y3C5 32814053
种属内
GPR141 Q7Z602 PMP22 Homo sapiens A0A6Q8PF08 32814053
种属内
GPR141 Q7Z602 PMP22 Homo sapiens A0A6Q8PF08 32814053
种属内
GPR141 Q7Z602 PMP22 Homo sapiens A0A6Q8PF08 32814053
种属内
GPR141 Q7Z602 SPRED1 Homo sapiens Q7Z699 32814053
种属内
GPR141 Q7Z602 SPRED1 Homo sapiens Q7Z699 32814053
种属内
GPR141 Q7Z602 SPRED1 Homo sapiens Q7Z699 32814053
种属内
GPR141 Q7Z602 TTR Homo sapiens P02766 32814053
种属内
GPR141 Q7Z602 TTR Homo sapiens P02766 32814053
种属内
GPR141 Q7Z602 TTR Homo sapiens P02766 32814053
种属内
GPR141 Q7Z602 WFS1 Homo sapiens O76024 32814053
种属内
GPR141 Q7Z602 WFS1 Homo sapiens O76024 32814053
种属内
GPR141 Q7Z602 WFS1 Homo sapiens O76024 32814053
种属间: 跨种属相互作用 种属内: 同种属相互作用

关联疾病

疾病名称 别名
Diamond-Blackfan Anemia 4

DBA4

Rps17-Related Diamond-Blackfan Anemia

Anemia, Diamond-Blackfan, Type 4

Townes-Brocks Syndrome

Townes Syndrome

Renal-Ear-Anal-Radial Syndrome

Anus, Imperforate, With Hand, Foot And Ear Anomalies

Imperforate Anus-Hand, Foot And Ear Anomalies Syndrome

Rear Syndrome

Sensorineural Deafness With Imperforate Anus And Hypoplastic Thumbs

Tbs

Deafness, Sensorineural, With Imperforate Anus And Hypoplastic Thumbs

Imperforate Anus With Hand, Foot And Ear Anomalies

Anal-Ear-Renal-Radial Malformation Syndrome

Deafness-Imperforate Anus-Hypoplastic Thumbs Syndrome

Imperforate Anus-Hand And Foot Anomalies Syndrome

Sensorineural Deafness-Imperforate Anus-Hypoplastic Thumbs Syndrome

Sensorineural Hearing Loss With Imperforate Anus And Hypoplastic Thumbs

疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

直系同源

种属 基因名 来源 基因 ID
Felis catus GPR141 VGNC VGNC:62675
Mus musculus GPR141 MGD MGI:2672983
Macaca mulatta GPR141 VGNC VGNC:81323
Canis familiaris GPR141 VGNC VGNC:41401
Bos taurus GPR141 VGNC VGNC:52783
Rattus norvegicus GPR141 RGD RGD:727906