IL13RA2 - interleukin 13 receptor subunit alpha 2 Gene

中文名称：白细胞介素 13 受体亚基 α 2

种属: Homo sapiens

同用名: CT19; IL-13R; IL13BP; CD213A2

基因 ID: 3598 | 基因类型: protein coding

关于 IL13RA2

Cytogenetic location: Xq23 Genomic coordinates (GRCh38): X:115,003,982-115,017,616 (from NCBI)

This gene has 3 transcripts (splice variants), 194 orthologues and 23 paralogues. Biased expression in testis (RPKM 16.6), appendix (RPKM 2.7) and 6 other tissues.

功能概要

该基因编码的蛋白质与 Il13RA1 密切相关，IL13RA1 是白细胞介素 13 受体复合物的一个亚单位。该蛋白以高亲和力结合 IL13，但缺乏细胞质结构域，并且似乎不作为信号介质发挥作用。据报道，它在 IL13 的内化中发挥作用。[RefSeq 提供，2008 年 7 月]

The protein encoded by this gene is closely related to Il13RA1, a subuint of the interleukin 13 receptor complex. This protein binds IL13 with high affinity, but lacks cytoplasmic domain, and does not appear to function as a signal mediator. It is reported to play a role in the internalization of IL13. [provided by RefSeq, Jul 2008]

IL13RA2 基因产物(1)

mRNA	Protein	Name
NM_000640.3	NP_000631.1	interleukin-13 receptor subunit alpha-2 precursor

基因本体论

分子功能

分子功能 GO 注释	逻辑证据	参考文献	来源
enables protein binding	IPI IPI: 通过物理相互作用推断	20223216	GOA

EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

IL13RA2 蛋白结构

IL6Ra-bind

0
100
200
300
380 a.a.

蛋白主名

其他名称

interleukin-13 receptor subunit alpha-2

IL-13 receptor subunit alpha-2

IL13RA2 蛋白互作信息

分类	蛋白名称	蛋白编号	互作蛋白	互作蛋白种属	互作蛋白编号	实验方法	参考文献
Intra	IL13RA2	Q14627	LGALS3	Homo sapiens	P17931	Anti Bait CoIP	29427412
Intra	IL13RA2	Q14627	PLPP6	Homo sapiens	Q8IY26	Validated Y2H	32296183
Intra	IL13RA2	Q14627	IL13	Homo sapiens	P35225	Anti Bait CoIP	27629921
Intra	IL13RA2	Q14627	IL13	Homo sapiens	P35225	Anti Bait CoIP	23972995
Intra	IL13RA2	Q14627	TMEM219	Homo sapiens	Q86XT9	Anti Bait CoIP	27629921
Intra	IL13RA2	Q14627	TMEM219	Homo sapiens	Q86XT9	Y2H	27629921
Intra	IL13RA2	Q14627	TMEM219	Homo sapiens	Q86XT9	Anti Bait CoIP	29427412
Intra	IL13RA2	Q14627	TMEM219	Homo sapiens	Q86XT9	BiFC	27629921
Intra	IL13RA2	Q14627	CHI3L1	Homo sapiens	P36222	Anti Tag CoIP	23972995

种属间: 跨种属相互作用 种属内: 同种属相互作用

重组 IL13RA2 蛋白

目录号	产品名	蛋白编号	纯度
HY-P75827	IL-13R alpha 2 Protein, Human (HEK293, His)	Q14627/NP_000631.1 (D27-L342)	≥95%
HY-P75829	IL-13R alpha 2 Protein, Human (Biotinylated, HEK293, His)	Q14627/NP_000631.1 (D27-L342)	≥95%

关联疾病

疾病名称

别名

Interstitial Lung Disease

Ild	Lung Diseases, Interstitial
Lung Diseases Interstitial	Interstitial Lung Diseases

Glioblastoma

Glioblastoma Multiforme	Gbm
Adult Glioblastoma Multiforme	Grade Iv Adult Astrocytic Tumor
Primary Glioblastoma Multiforme	Spongioblastoma Multiforme
Adult Glioblastoma	Primary Glioblastoma

Brain Cancer

Adult Brain Tumor	Malignant Neoplasm Of Brain
Brain Neoplasms	Brain Neoplasm
Neoplasm Of Brain	Primary Malignant Neoplasm Of Brain
Brain Tumors	Adult Malignant Brain Neoplasm
Brain Neoplasm, Adult	Bt - Brain Tumour
Malignant Brain Tumour	Malignant Primary Brain Neoplasm
Malignant Primary Brain Tumor	Malignant Tumor Of Adult Brain
Malignant Tumor Of Brain	Primary Brain Neoplasm
Primary Brain Tumor	Tumor Of The Brain
Brain Tumor, Adult	Brain Tumor Primary
Malignant Primary Brain Tumors	Primary Brain Tumors
Cancer, Brain	Brain Tumor, Primary

High Grade Glioma

Malignant Glioma	Glial Cell Tumor
Glioma, Malignant	Malignant Neuroglial Tumor
Neuroglial Tumor	Glioma
Malignant Gliomas

Medulloblastoma

MDB	Cpnet
Localized Primitive Neuroectodermal Tumor	Classic Medulloblastoma
Medulloblastoma Predisposition Syndrome	Medulloblastoma, Somatic
Brain Medulloblastoma	Cns Pnet
Infratentorial Primitive Neuroectodermal Tumor	Neuroectodermal Tumors, Primitive
Medulloblastomas	Desmoplastic Medulloblastoma
Medulloblastoma, With Extensive Nodularity	Medulloblastoma Of Unspecified Site
Medullomyoblastoma Of Unspecified Site

Granulomatous Disease, Chronic, Autosomal Recessive, 2

Chronic Granulomatous Disease Due To Deficiency Of Ncf-2	CGD2
Ncf2 Deficiency	P67-Phox Deficiency
Autosomal Recessive Chronic Granulomatous Disease Cytochrome B-Positive Type Ii	Granulomatous Disease, Chronic, Autosomal Recessive, Cytochrome B-Positive, Type 2
Granulomatous Disease, Chronic, Autosomal Recessive, Cytochrome B-Positive, Type Ii	Cgd, Autosomal Recessive Cytochrome B-Positive, Type Ii
Granulomatous Disease, Chronic, Due To Ncf2 Deficiency	Neutrophil Cytosol Factor 2 Deficiency
Chronic Granulomatous Disease 2, Autosomal Recessive	Autosomal Recessive Chronic Granulomatous Disease 2
Cdg2	Deficiency Of Ncf2
Deficiency Of P67-Phox	Chronic Granulomatous Disease Autosomal Recessive Cytochrome B-Positive Type Ii
Deficiency Of Neutrophil Cytosol Factor 2	Avellino Corneal Dystrophy

Asthma

Chronic Obstructive Asthma	Asthma, Diminished Response To Antileukotriene Treatment In
Bronchial Hyperreactivity	Asthma, Susceptibility To
Asthma, Bronchial	Asthma, Protection Against
Asthma, Nocturnal, Susceptibility To	Nocturnal Asthma
Asthma-Related Traits	Asthma-Related Traits, Susceptibility To
Asthma, Nocturnal	Chronic Obstructive Asthma With Acute Exacerbation
Chronic Obstructive Asthma With Status Asthmaticus	Exercise Induced Asthma
Exercise-Induced Asthma	Bronchial Asthma
Asthma, Exercise-Induced	Idiosyncratic Asthma
Unspecified Asthma With Acute Exacerbation	Asthma, Unspecified, With Stated Status Asthmaticus
Status Asthmaticus Nos	Acute Severe Asthma
Acute Severe Bronchial Asthma	Status Asthma
Status Post Asthmaticus

Renal Cell Carcinoma, Nonpapillary

Renal Cell Carcinoma	RCC
Nonpapillary Renal Cell Carcinoma	Clear Cell Renal Cell Carcinoma
Hypernephroma	Adenocarcinoma Of Kidney
Renal Carcinoma, Chromophobe, Somatic	Clear Cell Carcinoma Of Kidney
Clear-Cell Metastatic Renal Cell Carcinoma	Clear Cell Renal Carcinoma
Renal Cell Carcinoma, Somatic	Conventional Renal Cell Carcinoma
Conventional Renal Cell Carcinoma	Renal Clear Cell Carcinoma
Ccrcc	Hereditary Clear Cell Renal Cell Carcinoma
Carcinoma, Renal Cell	Renal Cell Carcinoma, Clear Cell, Somatic
Renal Cell Carcinoma, Clear Cell	Clear Cell Kidney Carcinoma
Clear Cell Rcc	Cystic-Multilocular Variant
Clear Cell Renal Cell Adenocarcinoma	Hereditary Clear Cell Renal Cell Adenocarcinoma
Common Renal Cell Carcinoma	Crcc
Renal Cell Carcinoma Non-Papillary	Carcinoma Renal Cell
Renal Cell Cancer	Carcinoma, Renal Cell, Nonpapillary

疾病名称	别名
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Cat. No.	产品名	作用方式	纯度	是否罕见病
HY-P10292	NOTA-Pep-1L		/	否
HY-RS06689	IL13RA2 Human Pre-designed siRNA Set A	Pre-designed Sets	/	否

直系同源

种属	基因名	来源	基因 ID
Macaca mulatta	IL13RA2	VGNC	VGNC:73709
Bos taurus	IL13RA2	VGNC	VGNC:30115
Mus musculus	IL13RA2	MGD	MGI:1277954
Rattus norvegicus	IL13RA2	RGD	RGD:620838
Canis familiaris	IL13RA2	VGNC	VGNC:41938
Felis catus	IL13RA2	VGNC	VGNC:67759
Others	IL13RA2	NCBI

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站点地图隐私声明

沪ICP备15051369号-4

上海工商

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沪(浦)应急管危经许[2021]201709(QFYS)

营业执照（三证合一）

IL13RA2 - interleukin 13 receptor subunit alpha 2 Gene

关于 IL13RA2

功能概要

IL13RA2 基因产物(1)

IL13RA2 蛋白结构

IL13RA2 蛋白互作信息

重组 IL13RA2 蛋白

关联疾病

直系同源

热门区域

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IL13RA2 - interleukin 13 receptor subunit alpha 2 Gene

关于 IL13RA2

功能概要

IL13RA2 基因产物(1)

IL13RA2 蛋白结构

IL13RA2 蛋白互作信息

重组 IL13RA2 蛋白

关联疾病

相关产品

直系同源

热门区域

A

B

C

F

G

H

J

L

N

Q

S

T

X

Y

Z