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  3. Dnajb1 - DnaJ heat shock protein family (Hsp40) member B1 Gene

Dnajb1 - DnaJ heat shock protein family (Hsp40) member B1 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

中文名称：DnaJ 热休克蛋白家族 (Hsp40) 成员 B1

种属: Rattus norvegicus

基因 ID: 361384 | 基因类型: protein coding

关于 Dnajb1

Primary_assembly 19: 24,522,717-24,526,458 reverse strand.mRatBN7.2:CM026992.1

This gene has 1 transcript (splice variant), 432 orthologues and 15 paralogues. Biased expression in Testes (RPKM 393.), Adrenal (RPKM 23.5) and 9 other tissues.

功能概要

预计该基因编码的蛋白可启动多种功能，包括 ATPase 结合活动； HSP70 蛋白结合活性；和伴侣结合活性。参与前脑发育。位于多个细胞成分中，包括树突棘；突触后细胞质；和精子头。在谷氨酸能突触和突触后密度中活跃。与人类 DNAJB1（DnaJ 热休克蛋白家族 (HSP40) 成员 B1）同源。 [由基因组资源联盟提供，2022 年 4 月]

Predicted to enable several functions, including ATPase binding activity; HSP70 protein binding activity; and chaperone binding activity. Involved in forebrain development. Located in several cellular components, including dendritic spine; postsynaptic cytosol; and sperm head. Is active in glutamatergic synapse and postsynaptic density. Orthologous to human DNAJB1 (DnaJ heat shock protein family (HSP40) member B1). [provided by Alliance of Genome Resources, Apr 2022]

Dnajb1 基因产物(1)

mRNA Protein Name
NM_001395149.1 NP_001382078.1 dnaJ homolog subfamily B member 1
基因本体论
  • 生物过程
  • 细胞组分
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in forebrain development IEP
IEP: 通过表达模式推断
9878698 RGD
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in dendritic spine IDA
IDA: 通过直接分析推断
9878698 RGD
is active in glutamatergic synapse IDA
IDA: 通过直接分析推断
9878698 RGD
located in neuronal cell body IDA
IDA: 通过直接分析推断
9878698 RGD
is active in postsynapse IDA
IDA: 通过直接分析推断
9878698 RGD
is active in postsynaptic density IDA
IDA: 通过直接分析推断
9878698 RGD
located in sperm head IDA
IDA: 通过直接分析推断
16955402 RGD
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

Dnajb1 蛋白结构

DnaJ

DnaJ: COG0484 (0 - 339)

  • 0
  • 100
  • 200
  • 300
  • 340 a.a.
蛋白主名 其他名称

dnaJ homolog subfamily B member 1

DnaJ (Hsp40) homolog, subfamily B, member 1

相关产品

Pre-clinical Phase
生物活性分子 (4)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-150072 DS89002333 Inhibitor 99.87% 否
HY-RS03861 DNAJB1 Human Pre-designed siRNA Set A Pre-designed Sets / 否
HY-RS03862 Dnajb1 Mouse Pre-designed siRNA Set A Pre-designed Sets / 否
HY-RS03863 Dnajb1 Rat Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Dnajb1 NCBI NCBI:3337
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