2. Gene
  3. ARF3 - ADP ribosylation factor 3 Gene

ARF3 - ADP ribosylation factor 3 Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：ADP 核糖基化因子 3

种属: Homo sapiens

基因 ID: 377 | 基因类型: protein coding

关于 ARF3

Cytogenetic location: 12q13.12 Genomic coordinates (GRCh38): 12:48,935,723-48,957,487 (from NCBI)

This gene has 10 transcripts (splice variants), 253 orthologues and 30 paralogues. Ubiquitous expression in brain (RPKM 69.0), colon (RPKM 28.8) and 24 other tissues.

功能概要

ADP-核糖基化因子 3 (ARF3) 是人类 ARF 基因家族的成员。这些基因编码小的鸟嘌呤核苷酸结合蛋白，可刺激霍乱毒素的 ADP-核糖基转移酶活性，并在水泡运输中发挥作用，并作为磷脂酶 D 的激活剂。基因产物包括 6 种 ARF 蛋白和 11 种 ARF 样蛋白，构成一个家族 Ras 超家族的成员。 ARF 蛋白分为 I 类 (ARF1、ARF2 和 ARF3) 、II 类 (ARF4 和 ARF5) 和 III 类 (ARF6) ，每一类的成员共享一个共同的基因组织。[RefSeq 提供，2022 年 10 月]

ADP-ribosylation factor 3 (ARF3) is a member of the human ARF gene family. These genes encode small guanine nucleotide-binding proteins that stimulate the ADP-ribosyltransferase activity of cholera toxin and play a role in vesicular trafficking and as activators of Phospholipase D. The gene products include 6 ARF proteins and 11 ARF-like proteins and constitute one family of the Ras superfamily. The ARF proteins are categorized as class I (ARF1, ARF2,and ARF3), class II (ARF4 and ARF5) and class III (ARF6) and members of each class share a common gene organization. [provided by RefSeq, Oct 2022]

ARF3 基因产物(11)

mRNA Protein Name
NM_001412914.1 NP_001399843.1 ADP-ribosylation factor 3 isoform a
NM_001412915.1 NP_001399844.1 ADP-ribosylation factor 3 isoform a
NM_001412916.1 NP_001399845.1 ADP-ribosylation factor 3 isoform a
NM_001412918.1 NP_001399847.1 ADP-ribosylation factor 3 isoform a
NM_001412920.1 NP_001399849.1 ADP-ribosylation factor 3 isoform a
NM_001412926.1 NP_001399855.1 ADP-ribosylation factor 3 isoform a
NM_001412928.1 NP_001399857.1 ADP-ribosylation factor 3 isoform a
NM_001412930.1 NP_001399859.1 ADP-ribosylation factor 3 isoform a
NM_001412931.1 NP_001399860.1 ADP-ribosylation factor 3 isoform a
NM_001412932.1 NP_001399861.1 ADP-ribosylation factor 3 isoform b
NM_001659.3 NP_001650.1 ADP-ribosylation factor 3 isoform a

ARF3 蛋白结构

Arf

Arf: ADP-ribosylation factor family (7 - 176)

  • 0
  • 100
  • 181 a.a.
蛋白主名 其他名称

ADP-ribosylation factor 3

small GTP binding protein

重组 ARF3 蛋白

目录号 产品名 蛋白编号 纯度
HY-P75583 ARF3 Protein, Human (His) P61204 (M1-K181) ≥95%

关联疾病

疾病名称 别名
Pectus Excavatum

Funnel Chest

Congenital Pectus Excavatum
Scoliosis
Heart, Malformation Of
Dystonia

Dystonic Disease

Dystonic Disorder

Dystonia Disorders

Neuroleptic Dyskinesia
Heart Disease

Heart Failure

Congenital Heart Disease

Heart Diseases

Congenital Heart Defects

Congenital Heart Defect

Heart Malformation

Congenital Anomaly Of Heart

Heart Defect

Heart-Congenital Defect

Congenital Heart Disorder

Heart Defects Congenital

Heart Defects, Congenital

Heart Defects

Heart Disease, Congenital

Disease, Heart, Congenital

Congestive Heart Failure
Hypotonia
Microcephaly

Microencephaly

Microcephalus

Microcephalic

Nanocephaly

Congenital Microcephaly

Brain Hypoplasia

Brain Nondevelopment

Cephalic Hypoplasia

Undeveloped Cerebrum

Undeveloped Brain

Micrencephalon

Micrencephaly
Cholera

Vibrio Cholerae Infection

Cholera - Vibrio Cholerae

Cholera Due To Vibrio Cholerae

Vibrio Cholerae

Cholera Syndrome

Asiatic Cholera

Epidemic Cholera
Smith-Mccort Dysplasia 1

Smith-Mccort Dysplasia

SMC1

Smc

Smith Mccort Dysplasia

Smith-Mccort Dwarfism
Retinitis Pigmentosa 7

Leber Congenital Amaurosis 18

RP7

Retinitis Pigmentosa 7, Digenic Form

Retinitis Pigmentosa 7 And Digenic Form

Retinitis Pigmentosa 7, Digenic

LCA18

Retinitis Pigmentosa 7 Digenic
Dyggve-Melchior-Clausen Disease

Dyggve-Melchior-Clausen Syndrome

DMC

Dmc Disease

Pseudo-Morquio Disease Type I

Dmc Syndrome
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS00895 ARF3 Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Rattus norvegicus ARF3 RGD RGD:621273
Felis catus ARF3 VGNC VGNC:83498
Mus musculus ARF3 MGD MGI:99432
Others ARF3 NCBI
嗨！很高兴为您提供帮助！

尊敬的 MCE 客户您好，
请您选择所在区域，我们将转接对应客服为您服务！

热门区域

A

B

C

F

G

H

J

L

N

Q

S

T

X

Y

Z

热 A B C F G H J L N Q S T X Y Z