1. Gene
  2. Kash5 - KASH domain containing 5 Gene

Kash5 - KASH domain containing 5 Gene

种属: Mus musculus

同用名: Gm1434; Ccdc155

基因 ID: 384619 | 基因类型: protein coding

关于 Kash5

功能概要

Enables dynein complex binding activity and identical protein binding activity. Involved in Cytoskeleton organization; spindle localization; and telomere localization. Acts upstream of or within double-strand break repair via homologous recombination; gamete generation; and homologous chromosome segregation. Located in chromosome; meiotic spindle pole; and nuclear outer membrane. Part of meiotic nuclear membrane microtubule tethering complex. Is expressed in spermatocyte. Orthologous to human KASH5 (KASH domain containing 5). [provided by Alliance of Genome Resources, Apr 2022]

Kash5 基因产物(1)

mRNA Protein Name
NM_201374.2 NP_958762.2 protein KASH5
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables dynein complex binding IDA
IDA: 通过直接分析推断
24062341 MGI
enables identical protein binding IDA
IDA: 通过直接分析推断
24062341 MGI
enables protein binding IPI
IPI: 通过物理相互作用推断
22826121 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in actin filament organization IMP
IMP: 通过突变表型推断
26842404 MGI
acts upstream of or within chromosome localization to nuclear envelope involved in homologous chromosome segregation IMP
IMP: 通过突变表型推断
24062341 MGI
acts upstream of or within double-strand break repair via homologous recombination IMP
IMP: 通过突变表型推断
24062341 MGI
acts upstream of or within homologous chromosome pairing at meiosis IMP
IMP: 通过突变表型推断
24062341 MGI
acts upstream of or within meiotic telomere clustering IPI
IPI: 通过物理相互作用推断
24062341 MGI
acts upstream of or within oogenesis IMP
IMP: 通过突变表型推断
24062341 MGI
acts upstream of or within spermatogenesis IMP
IMP: 通过突变表型推断
24062341 MGI
involved in spindle assembly IDA
IDA: 通过直接分析推断
26842404 MGI
involved in spindle localization IDA
IDA: 通过直接分析推断
26842404 MGI
involved in telomere localization IMP
IMP: 通过突变表型推断
25892231 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in chromosome, telomeric region IDA
IDA: 通过直接分析推断
22826121 MGI
located in lateral element IDA
IDA: 通过直接分析推断
24062341 MGI
part of meiotic nuclear membrane microtubule tethering complex IDA
IDA: 通过直接分析推断
24062341 MGI
located in meiotic spindle pole IDA
IDA: 通过直接分析推断
26842404 MGI
located in nuclear outer membrane IDA
IDA: 通过直接分析推断
24062341 MGI
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

protein KASH5

KASH domain-containing protein 5

coiled-coil domain containing 155

coiled-coil domain-containing protein 155

Kash5 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
种属内
Kash5 Q80VJ8 Sun1 Mus musculus Q9D666
IF
22826121
种属内
Kash5 Q80VJ8 Sun1 Mus musculus Q9D666
Anti Bait CoIP
22826121
种属间: 跨种属相互作用 种属内: 同种属相互作用

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Kash5 NCBI NCBI:147872