1. Gene
  2. CLEC2A - C-type lectin domain family 2 member A Gene

CLEC2A - C-type lectin domain family 2 member A Gene

中文名称:C 型凝集素域家族 2 成员 A

种属: Homo sapiens

同用名: KACL; PILAR; UNQ5792; INPE5792

基因 ID: 387836 | 基因类型: protein coding

关于 CLEC2A

Cytogenetic location: 12p13.31 Genomic coordinates (GRCh38): 12:9,877,742-9,932,370 (from NCBI)

This gene has 2 transcripts (splice variants), 315 orthologues and 23 paralogues. Restricted expression toward skin (RPKM 6.7).

功能概要

CLEC2A 属于激活诱导的自然杀伤基因复合物编码的 C 型凝集素样受体的 CLEC2 家族 (Spreu 等人,2007 [PubMed 18046548]) 。[OMIM 提供,2008 年 5 月]

CLEC2A belongs to the CLEC2 family of activation-induced, natural killer gene complex-encoded C-type lectin-like receptors (Spreu et al., 2007 [PubMed 18046548]).[supplied by OMIM, May 2008]

CLEC2A 基因产物(2)

mRNA Protein Name
NM_001130711.2 NP_001124183.1 C-type lectin domain family 2 member A isoform 1
NM_207375.3 NP_997258.1 C-type lectin domain family 2 member A isoform 2
基因本体论
  • 分子功能
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
20194751 GOA
enables protein homodimerization activity IDA
IDA: 通过直接分析推断
20194751 GOA
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断

CLEC2A 蛋白结构

Lectin_C

Lectin_C: Lectin C-type domain (76 - 135)

  • 0
  • 100
  • 174 a.a.
蛋白主名 其他名称

C-type lectin domain family 2 member A

keratinocyte-associated C-type lectin

CLEC2A 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
Intra CLEC2A Q6UVW9 HIBADH Homo sapiens P31937
Y2H Prey Pooling
32296183
Intra CLEC2A Q6UVW9 HIBADH Homo sapiens P31937
Y2H Array
32296183
Intra CLEC2A Q6UVW9 GPX8 Homo sapiens Q8TED1
Y2H Array
32296183
Intra CLEC2A Q6UVW9 GPX8 Homo sapiens Q8TED1
Y2H Prey Pooling
32296183
Intra CLEC2A Q6UVW9 GPX8 Homo sapiens Q8TED1
Validated Y2H
32296183
Intra CLEC2A Q6UVW9 CLEC2D Homo sapiens Q9UHP7-3
Validated Y2H
32296183
Intra CLEC2A Q6UVW9 CLEC2D Homo sapiens Q9UHP7-3
Y2H Array
32296183
Intra CLEC2A Q6UVW9 CLEC2D Homo sapiens Q9UHP7-3
Y2H Prey Pooling
32296183
Intra CLEC2A Q6UVW9 TEX29 Homo sapiens Q8N6K0
Validated Y2H
32296183
Intra CLEC2A Q6UVW9 TEX29 Homo sapiens Q8N6K0
Y2H Prey Pooling
32296183
Intra CLEC2A Q6UVW9 TEX29 Homo sapiens Q8N6K0
Y2H Array
32296183
种属间: 跨种属相互作用 种属内: 同种属相互作用

关联疾病

疾病名称 别名
Pilar Sheath Acanthoma

Acanthoma, Pilar Sheath

Lichen Nitidus

Pinkus' Disease

疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

直系同源

种属 基因名 来源 基因 ID
Macaca mulatta CLEC2A VGNC VGNC:71329
Mus musculus CLEC2A MGD MGI:3522133
Rattus norvegicus CLEC2A RGD RGD:1588698