1. Gene
  2. Flrt2 - fibronectin leucine rich transmembrane protein 2 Gene

Flrt2 - fibronectin leucine rich transmembrane protein 2 Gene

种属: Mus musculus

基因 ID: 399558 | 基因类型: protein coding

关于 Flrt2

功能概要

Enables chemorepellent activity and Fibroblast Growth Factor receptor binding activity. Involved in basement membrane organization; cell adhesion involved in heart morphogenesis; and Fibroblast Growth Factor receptor signaling pathway. Acts upstream of or within axon guidance; positive regulation of synapse assembly; and regulation of neuron migration. Located in cell-cell junction and extracellular space. Is integral component of plasma membrane. Colocalizes with focal adhesion. Is expressed in several structures, including alimentary system epithelium; branchial arch; central nervous system; embryo mesenchyme; and sensory organ. Orthologous to human FLRT2 (fibronectin leucine rich transmembrane protein 2). [provided by Alliance of Genome Resources, Apr 2022]

Flrt2 基因产物(1)

mRNA Protein Name
NM_201518.4 NP_958926.1 leucine-rich repeat transmembrane protein FLRT2 precursor
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables chemorepellent activity IDA
IDA: 通过直接分析推断
21673655 MGI
enables fibroblast growth factor receptor binding IPI
IPI: 通过物理相互作用推断
16872596 MGI
enables protein binding IPI
IPI: 通过物理相互作用推断
21673655 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within axon guidance IGI
IGI: 通过遗传相互作用推断
21673655 MGI
involved in basement membrane organization IMP
IMP: 通过突变表型推断
21350012 MGI
involved in cell adhesion involved in heart morphogenesis IMP
IMP: 通过突变表型推断
21350012 MGI
involved in fibroblast growth factor receptor signaling pathway IMP
IMP: 通过突变表型推断
16872596 MGI
involved in heart morphogenesis IMP
IMP: 通过突变表型推断
21350012 MGI
acts upstream of or within positive regulation of synapse assembly IDA
IDA: 通过直接分析推断
24613359 MGI
acts upstream of or within regulation of neuron migration IGI
IGI: 通过遗传相互作用推断
21673655 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in cell-cell junction IDA
IDA: 通过直接分析推断
16872596 MGI
located in extracellular space IDA
IDA: 通过直接分析推断
21673655 MGI
colocalizes with focal adhesion IDA
IDA: 通过直接分析推断
16872596 MGI
is active in glutamatergic synapse IDA
IDA: 通过直接分析推断
34744626 MGI
located in plasma membrane IDA
IDA: 通过直接分析推断
16872596 MGI
is active in postsynaptic membrane IDA
IDA: 通过直接分析推断
34744626 MGI
is active in presynaptic membrane IDA
IDA: 通过直接分析推断
34744626 MGI
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

leucine-rich repeat transmembrane protein FLRT2

重组 Flrt2 蛋白

目录号 产品名 蛋白编号 纯度
HY-P76934 FLRT2 Protein, Mouse (HEK293, His) Q8BLU0 (C36-S539) ≥95%

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Flrt2 NCBI NCBI:23768