1. Gene
  2. LY6H - lymphocyte antigen 6 family member H Gene

LY6H - lymphocyte antigen 6 family member H Gene

中文名称:淋巴细胞抗原 6 家族成员 H

种属: Homo sapiens

同用名: NMLY6

基因 ID: 4062 | 基因类型: protein coding

关于 LY6H

Cytogenetic location: 8q24.3 Genomic coordinates (GRCh38): 8:143,157,916-143,160,654 (from NCBI)

This gene has 5 transcripts (splice variants), 1 gene allele, 86 orthologues and 1 paralogue. Biased expression in brain (RPKM 15.6), stomach (RPKM 1.2) and 1 other tissue.

功能概要

预测具有乙酰胆碱受体结合活性和乙酰胆碱受体抑制剂活性。预测参与乙酰胆碱受体信号通路。预测位于细胞外区域。预计在质膜上有活性。 [由基因组资源联盟提供,2022 年 4 月]

Predicted to enable acetylcholine receptor binding activity and acetylcholine receptor inhibitor activity. Predicted to be involved in acetylcholine receptor signaling pathway. Predicted to be located in extracellular region. Predicted to be active in plasma membrane. [provided by Alliance of Genome Resources, Apr 2022]

LY6H 基因产物(3)

mRNA Protein Name
NM_001130478.2 NP_001123950.1 lymphocyte antigen 6H isoform b precursor
NM_001135655.2 NP_001129127.1 lymphocyte antigen 6H isoform b precursor
NM_002347.5 NP_002338.3 lymphocyte antigen 6H isoform a precursor
基因本体论
  • 分子功能
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
25416956 GOA
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断

LY6H 蛋白结构

UPAR_LY6

UPAR_LY6: u-PAR/Ly-6 domain (28 - 111)

  • 0
  • 100
  • 140 a.a.
蛋白主名 其他名称

lymphocyte antigen 6H

ly-6H

重组 LY6H 蛋白

目录号 产品名 蛋白编号 纯度
HY-P70217 Lymphocyte antigen 6H/LY6H Protein, Human (HEK293, His) O94772 (L26-G115) ≥95%

关联疾病

疾病名称 别名
Variola Minor

Alastrim

Cottonpox

Milkpox

Whitepox

Vertebral Artery Occlusion

Occlusion And Stenosis Of Vertebral Artery

疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

直系同源

种属 基因名 来源 基因 ID
Macaca mulatta LY6H VGNC VGNC:74462
Mus musculus LY6H MGD MGI:1346030
Felis catus LY6H VGNC VGNC:81669
Canis familiaris LY6H VGNC VGNC:51776
Rattus norvegicus LY6H RGD RGD:1311896
Bos taurus LY6H VGNC VGNC:31091
Others LY6H NCBI