2. Gene
  3. ASTL - astacin like metalloendopeptidase Gene

ASTL - astacin like metalloendopeptidase Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：虾青素样金属内肽酶

种属: Homo sapiens

同用名: SAS1B; OOMD11

基因 ID: 431705 | 基因类型: protein coding

关于 ASTL

Cytogenetic location: 2q11.2 Genomic coordinates (GRCh38): 2:96,122,818-96,138,564 (from NCBI)

This gene has 2 transcripts (splice variants), 210 orthologues, 35 paralogues and is associated with 1 phenotype. Biased expression in bone marrow (RPKM 1.1), skin (RPKM 0.2) and 10 other tissues.

功能概要

预测启用天冬氨酸型肽酶活性；谷氨酸型肽酶活性；和金属内肽酶活性。预计参与多个过程，包括对精子与透明带结合活性的负调节；蛋白质加工的正调节；和预防多精症。预测位于皮质颗粒和质膜。 [由基因组资源联盟提供，2022 年 4 月]

Predicted to enable aspartic-type peptidase activity; glutamic-type peptidase activity; and metalloendopeptidase activity. Predicted to be involved in several processes, including negative regulation of binding activity of sperm to zona pellucida; positive regulation of protein processing; and prevention of polyspermy. Predicted to be located in cortical granule and plasma membrane. [provided by Alliance of Genome Resources, Apr 2022]

ASTL 基因产物(1)

mRNA Protein Name
NM_001002036.4 NP_001002036.3 astacin-like metalloendopeptidase precursor
基因本体论
  • 分子功能
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
32296183 GOA
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

ASTL 蛋白结构

Astacin

Astacin: Astacin (Peptidase family M12A) (103 - 282)

  • 0
  • 100
  • 200
  • 300
  • 400
  • 431 a.a.
蛋白主名 其他名称

astacin-like metalloendopeptidase

ZP2-proteinase

关联疾病

疾病名称 别名
Oocyte Maturation Defect 11

OOMD11
Colorado Tick Fever

Mountain Tick Fever

Tick Fever, American Mountain

American Mountain Fever

Colorado Tick Encephalitis

Colorado Tick-Borne Disease

Mountain Fever

American Mountain Tick Fever

Colorado Tick-Borne Fever

Colorado Tick Fever Virus

Non-Exanthematous Tick Fever
Powassan Encephalitis

Powassan Encephalitis Virus Infection
Anisakiasis

Infection By Anisakis Larva

Anisakis Infection

Pseudoterranova Infection

Anisakiasis Due To Anisakis Simplex

Anisakiasis Due To Pseudoterranova Decipiens

Anisakis Infestation

Infection Due To Anisakis Larvae
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS01111 ASTL Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Rattus norvegicus ASTL RGD RGD:1562279
Mus musculus ASTL MGD MGI:3046414
Macaca mulatta ASTL VGNC VGNC:106129
Felis catus ASTL VGNC VGNC:59982
Bos taurus ASTL VGNC VGNC:26226
Others ASTL NCBI
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