2. Gene
  3. RHEX - regulator of hemoglobinization and erythroid cell expansion Gene

RHEX - regulator of hemoglobinization and erythroid cell expansion Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品

中文名称：血红蛋白化和红细胞扩张的调节因子

种属: Homo sapiens

同用名: C1orf186

基因 ID: 440712 | 基因类型: protein coding

关于 RHEX

Cytogenetic location: 1q32.1 Genomic coordinates (GRCh38): 1:206,053,173-206,102,449 (from NCBI)

This gene has 5 transcripts (splice variants) and 71 orthologues. Broad expression in endometrium (RPKM 4.0), gall bladder (RPKM 2.3) and 16 other tissues.

功能概要

启用促红细胞生成素受体结合活性。参与促红细胞生成素介导的信号通路和红细胞分化的正调控。位于质膜。 [由基因组资源联盟提供，2022 年 4 月]

Enables erythropoietin receptor binding activity. Involved in erythropoietin-mediated signaling pathway and positive regulation of erythrocyte differentiation. Located in plasma membrane. [provided by Alliance of Genome Resources, Apr 2022]

RHEX 基因产物(2)

mRNA Protein Name
NM_001007544.4 NP_001007545.1 regulator of hemoglobinization and erythroid cell expansion protein
NM_001369490.1 NP_001356419.1 regulator of hemoglobinization and erythroid cell expansion protein
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables erythropoietin receptor binding IDA
IDA: 通过直接分析推断
25092874 GOA
enables protein binding IPI
IPI: 通过物理相互作用推断
25092874 GOA
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in cellular response to erythropoietin IMP
IMP: 通过突变表型推断
25092874 GOA
involved in erythropoietin-mediated signaling pathway IMP
IMP: 通过突变表型推断
25092874 GOA
involved in positive regulation of erythrocyte differentiation IMP
IMP: 通过突变表型推断
25092874 GOA
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in plasma membrane IDA
IDA: 通过直接分析推断
25092874 GOA
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

regulator of hemoglobinization and erythroid cell expansion protein

regulator of human erythroid cell expansion protein

RHEX 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
Intra RHEX Q6ZWK4 SH3GLB1 Homo sapiens Q9Y371
Validated Y2H
32296183
Intra RHEX Q6ZWK4 RBFA Homo sapiens Q8N0V3
Validated Y2H
32296183
Intra RHEX Q6ZWK4 SH3GL1 Homo sapiens Q99961
Validated Y2H
32296183
Intra RHEX Q6ZWK4 PBX3 Homo sapiens Q96AL5
Validated Y2H
32296183
种属间: 跨种属相互作用 种属内: 同种属相互作用

关联疾病

疾病名称 别名
Gallbladder Benign Neoplasm
Gallbladder Adenoma
Biliary Tract Benign Neoplasm

Extrahepatic Bile Duct Neoplasm

Neoplasm Of Extrahepatic Bile Ducts

Tumor Of The Extrahepatic Bile Duct
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS11943 RHEX Human Pre-designed siRNA Set A Pre-designed Sets / 否
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