2. Gene
  3. OPRD1 - opioid receptor delta 1 Gene

OPRD1 - opioid receptor delta 1 Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：阿片受体δ1

种属: Homo sapiens

同用名: DOP; DOR; DOR1; OPRD

基因 ID: 4985 | 基因类型: protein coding

关于 OPRD1

Cytogenetic location: 1p35.3 Genomic coordinates (GRCh38): 1:28,812,170-28,871,267 (from NCBI)

This gene has 1 transcript (splice variant), 253 orthologues and 17 paralogues. Low expression observed in reference dataset.

功能概要

启用 G 蛋白偶联脑啡肽受体活性。参与多个过程，包括 G 蛋白偶联的阿片受体信号通路；细胞对缺氧的反应；和肽基丝氨酸磷酸化的正调节。是质膜的固有成分。 [由基因组资源联盟提供，2022 年 4 月]

Enables G protein-coupled enkephalin receptor activity. Involved in several processes, including G protein-coupled Opioid Receptor signaling pathway; cellular response to hypoxia; and positive regulation of peptidyl-serine phosphorylation. Is intrinsic component of plasma membrane. [provided by Alliance of Genome Resources, Apr 2022]

OPRD1 基因产物(1)

mRNA Protein Name
NM_000911.4 NP_000902.3 delta-type opioid receptor

OPRD1 蛋白结构

7tm_1

7tm_1: 7 transmembrane receptor (rhodopsin family) (66 - 318)

  • 0
  • 100
  • 200
  • 300
  • 372 a.a.
蛋白主名 其他名称

delta-type opioid receptor

D-OR-1

OPRD1 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
Intra OPRD1 P41143 SMAGP Homo sapiens Q0VAQ4
Validated Y2H
32296183
Intra OPRD1 P41143 RPRM Homo sapiens Q9NS64
Validated Y2H
32296183
Intra OPRD1 P41143 TMEM237 Homo sapiens Q96Q45-2
Y2H Prey Pooling
32296183
Intra OPRD1 P41143 TMEM237 Homo sapiens Q96Q45-2
Validated Y2H
32296183
Intra OPRD1 P41143 TMEM237 Homo sapiens Q96Q45-2
Y2H Array
32296183
Intra OPRD1 P41143 CTXN3 Homo sapiens Q4LDR2
Validated Y2H
32296183
Intra OPRD1 P41143 SLC13A4 Homo sapiens Q9UKG4
Y2H Prey Pooling
32296183
Intra OPRD1 P41143 SLC13A4 Homo sapiens Q9UKG4
Validated Y2H
32296183
Intra OPRD1 P41143 SLC13A4 Homo sapiens Q9UKG4
Y2H Array
32296183
Intra OPRD1 P41143 SLC12A7 Homo sapiens Q9Y666-2
Validated Y2H
32296183
Intra OPRD1 P41143 CANX Homo sapiens P27824
Anti Tag CoIP
20528919
Intra OPRD1 P41143 ATP2A2 Homo sapiens P16615
Anti Tag CoIP
20528919
Cross OPRD1 P41143 ATP2A2 Sus scrofa P11607
Anti Tag CoIP
20528919
种属间: 跨种属相互作用 种属内: 同种属相互作用

关联疾病

疾病名称 别名
Morphine Dependence
Heroin Dependence
Neonatal Abstinence Syndrome

Drug Withdrawal Syndrome In Newborn
Drug Dependence
Opiate Dependence

Opioid Dependence

Opioid Addiction

Opiate Addiction

Opioid Type Dependence

Opioid-Related Disorders

Opium Dependence

Narcotic Dependence

Intravenous Narcotism

Narcotism Nos

Oral Narcotism Nos
Substance Dependence
Pertussis

Whooping Cough

Bordetella Infections

Bordetella Infection

Bordetella Pertussis Infection

Wc - Whooping Cough

Whooping Cough Due To Unspecified Organism

Bordetellosis

Tussis Convulsiva

Whooping Cough, Unspecified Organism

Wc - [Whooping Cough]

Whooping Cough Due To B. Parapertussis

Infection Due To Bordetella Parapertussis
Opioid Abuse

Opioid-Related Disorders
Alcohol Dependence

Alcoholism

Alcohol Dependence, Susceptibility To

Alcohol Dependence, Protection Against

Aerodigestive Tract Cancer, Squamous Cell, Alcohol-Related, Protection Against

Alcoholism, Susceptibility To

Alcoholic Intoxication, Chronic

Pharyngeal Neoplasms

Chronic Alcoholism

Dipsomania

Alcohol Addiction

Ethanol Dependence

Chronic Ethanolism

Chronic Alcoholic Disease Nos

Alcoholic Disease Nos

Alcoholic
Cocaine Dependence
Pain Agnosia

Analgesia
Agnosia

Dyspraxia

Primary Visual Agnosia

Dyspraxia Syndrome

Monomodal Visual Amnesia

Visual Amnesia

Agnosia, Primary Visual

Apraxias

Alexia
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (2)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS09801 OPRD1 Human Pre-designed siRNA Set A Pre-designed Sets / 否
HY-116163 ML350 / 否

直系同源

种属 基因名 来源 基因 ID
Mus musculus OPRD1 MGD MGI:97438
Felis catus OPRD1 VGNC VGNC:68632
Bos taurus OPRD1 VGNC VGNC:50539
Canis familiaris OPRD1 VGNC VGNC:44132
Macaca mulatta OPRD1 VGNC VGNC:75589
Rattus norvegicus OPRD1 RGD RGD:3233
Others OPRD1 NCBI
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