2. Gene
  3. G0S2 - G0/G1 switch 2 Gene

G0S2 - G0/G1 switch 2 Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：G0/G1 开关 2

种属: Homo sapiens

基因 ID: 50486 | 基因类型: protein coding

关于 G0S2

Cytogenetic location: 1q32.2 Genomic coordinates (GRCh38): 1:209,675,412-209,676,390 (from NCBI)

This gene has 1 transcript (splice variant) and 163 orthologues. Biased expression in fat (RPKM 569.0), bone marrow (RPKM 395.4) and 4 other tissues.

功能概要

参与外源性凋亡信号通路和外源性凋亡信号通路的正调控。位于线粒体中。 [由基因组资源联盟提供，2022 年 4 月]

Involved in extrinsic apoptotic signaling pathway and positive regulation of extrinsic apoptotic signaling pathway. Located in mitochondrion. [provided by Alliance of Genome Resources, Apr 2022]

G0S2 基因产物(1)

mRNA Protein Name
NM_015714.4 NP_056529.1 G0/G1 switch protein 2
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
19706769 GOA
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in extrinsic apoptotic signaling pathway IDA
IDA: 通过直接分析推断
19706769 GOA
involved in positive regulation of extrinsic apoptotic signaling pathway IDA
IDA: 通过直接分析推断
19706769 GOA
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in mitochondrion IDA
IDA: 通过直接分析推断
19706769 GOA
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

G0S2 蛋白结构

G0-G1_switch_2

G0-G1_switch_2: G0/G1 switch protein 2 (1 - 103)

  • 0
  • 103 a.a.
蛋白主名 其他名称

G0/G1 switch protein 2

G0/G1 switch regulatory protein 2

G0S2 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
种属内
G0S2 P27469 BCL2L2 Homo sapiens Q92843
Validated Y2H
32296183
种属内
G0S2 P27469 BCL2L1 Homo sapiens Q07817
Validated Y2H
32296183
种属间: 跨种属相互作用 种属内: 同种属相互作用

关联疾病

疾病名称 别名
Crohn'S Colitis

Crohn Disease
Hypothalamic Neoplasm

Hypothalamic Neoplasms

Neoplasm Of The Hypothalamus

Tumor Of Hypothalamus
Diencephalic Neoplasm

Malignant Diencephalic Neoplasm

Malignant Diencephalic Tumor

Tumor Of Diencephalon
Chanarin-Dorfman Syndrome

Neutral Lipid Storage Disease

CDS

Neutral Lipid Storage Disease With Ichthyosis

Triglyceride Storage Disease With Impaired Long-Chain Fatty Acid Oxidation

Triglyceride Storage Disease With Ichthyosis

Nlsdi

Ichthyotic Neutral Lipid Storage Disease

Dorfman-Chanarin Syndrome

Dcs

Chanarin-Dorfman Disease

Ichthyosiform Erythroderma With Leukocyte Vacuolation

Lipidosis With Triglyceride Storage Disease

Disorder Of Cornification 12

Dorfman Chanarin Syndrome

Neutral Lipid Storage Disease With Ichthyotic

Dorfman-Chanarin Disease
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (2)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-120897 NS-3-008 hydrochloride Inhibitor 99.65% 否
HY-RS05187 G0S2 Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Bos taurus G0S2 VGNC VGNC:29174
Felis catus G0S2 VGNC VGNC:107877
Mus musculus G0S2 MGD MGI:1316737
Macaca mulatta G0S2 VGNC VGNC:99957
Rattus norvegicus G0S2 RGD RGD:1311675
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