2. Gene
  3. PODXL2 - podocalyxin like 2 Gene

PODXL2 - podocalyxin like 2 Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：podocalyxin 样 2

种属: Homo sapiens

同用名: EG; PODLX2

基因 ID: 50512 | 基因类型: protein coding

关于 PODXL2

Cytogenetic location: 3q21.3 Genomic coordinates (GRCh38): 3:127,629,185-127,672,802 (from NCBI)

This gene has 1 transcript (splice variant) and 169 orthologues. Broad expression in brain (RPKM 27.2), testis (RPKM 16.2) and 16 other tissues.

功能概要

该基因是细胞表面跨膜蛋白 CD34 家族的成员，其特征在于 N 端细胞外粘蛋白结构域、球状和茎状结构域、单次跨膜区域和带电荷的细胞质尾部。编码的蛋白质是血管选择素的配体。[RefSeq 提供，2012 年 10 月]

This gene is a member of the CD34 family of cell surface transmembrane proteins, which are characterized by an N-terminal extracellular Mucin domain, globular and stalk domains, a single pass transmembrane region, and a charged cytoplasmic tail. The encoded protein is a ligand for vascular selectins. [provided by RefSeq, Oct 2012]

PODXL2 基因产物(1)

mRNA Protein Name
NM_015720.4 NP_056535.1 podocalyxin-like protein 2 precursor
基因本体论
  • 分子功能
  • 生物过程
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
18606703 GOA
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in leukocyte tethering or rolling IDA
IDA: 通过直接分析推断
18606703 GOA
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

PODXL2 蛋白结构

CD34_antigen

CD34_antigen: CD34/Podocalyxin family (393 - 605)

  • 0
  • 100
  • 200
  • 300
  • 400
  • 500
  • 605 a.a.
蛋白主名 其他名称

podocalyxin-like protein 2

endoglycan

重组 PODXL2 蛋白

目录号 产品名 蛋白编号 纯度
HY-P78020 Endoglycan/PODXL2 Protein, Human (HEK293, His) Q9NZ53-1 (G33-T500) ≥95%

关联疾病

疾病名称 别名
Homocystinuria-Megaloblastic Anemia, Cblg Complementation Type

Methylcobalamin Deficiency, Cblg Type

HMAG

Methionine Synthase Deficiency

Methylcobalamin Deficiency Type Cblg

Homocystinuria-Megaloblastic Anemia Due To Defect In Cobalamin Metabolism, Cblg Complementation Type

Homocystinuria-Megaloblastic Anemia Cblg Type

Homocystinuria-Megaloblastic Anemia Due To Defect In Cobalamin Metabolism Cblg Complementation Type

Methylcobalamin Deficiency Cbl G Type

Homocystinuria Due To Defect In Methylation Cbl G

Cblg

Functional Methionine Synthase Deficiency Type Cblg

Methylcobalamin Deficiency Cblg Type

Arakawa Syndrome 2
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS10809 PODXL2 Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Canis familiaris PODXL2 VGNC VGNC:44765
Macaca mulatta PODXL2 VGNC VGNC:76056
Felis catus PODXL2 VGNC VGNC:64275
Rattus norvegicus PODXL2 RGD RGD:1305815
Bos taurus PODXL2 VGNC VGNC:33103
Mus musculus PODXL2 MGD MGI:2442488
Others PODXL2 NCBI
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