MED31 - mediator complex subunit 31 Gene

中文名称：介体复合体亚基 31

种属: Homo sapiens

同用名: Soh1; CGI-125; 3110004H13Rik

基因 ID: 51003 | 基因类型: protein coding

关于 MED31

This gene has 4 transcripts (splice variants) and 195 orthologues. Ubiquitous expression in brain (RPKM 6.0), adrenal (RPKM 4.6) and 25 other tissues.

功能概要

预测可实现转录共调节因子活性和泛素蛋白连接酶活性。预计参与 RNA 聚合酶 II 的转录调控。预计在肢体发育的上游或之内起作用，并对成纤维细胞增殖进行负调节。预测位于核质中。预计是核心介体复合体和介体复合体的一部分。 [由基因组资源联盟提供，2022 年 4 月]

Predicted to enable transcription coregulator activity and ubiquitin protein Ligase activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to act upstream of or within limb development and negative regulation of fibroblast proliferation. Predicted to be located in nucleoplasm. Predicted to be part of core mediator complex and mediator complex. [provided by Alliance of Genome Resources, Apr 2022]

MED31 基因产物(1)

mRNA	Protein	Name
NM_016060.3	NP_057144.1	mediator of RNA polymerase II transcription subunit 31

基因本体论

分子功能
细胞组分

分子功能 GO 注释	逻辑证据	参考文献	来源
enables protein binding	IPI IPI: 通过物理相互作用推断	15383276	GOA

细胞组分 GO 注释	逻辑证据	参考文献	来源
part of core mediator complex	IPI IPI: 通过物理相互作用推断	24882805	GOA
located in nucleus	IDA IDA: 通过直接分析推断	24882805	GOA

EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

MED31 蛋白结构

Med31

0
100
131 a.a.

蛋白主名

其他名称

mediator of RNA polymerase II transcription subunit 31

hSOH1

MED31 蛋白互作信息

分类	蛋白名称	蛋白编号	互作蛋白	互作蛋白种属	互作蛋白编号	实验方法	参考文献
种属内	MED31	Q9Y3C7	MED7	Homo sapiens	O43513	Anti Tag CoIP	35271311
种属内	MED31	Q9Y3C7	GADD45G	Homo sapiens	O95257	Pull Down	15383276
种属内	MED31	Q9Y3C7	HTT	Homo sapiens	P42858	Pull Down	15383276
种属内	MED31	Q9Y3C7	HTT	Homo sapiens	P42858	Y2H Array	32814053

种属间: 跨种属相互作用 种属内: 同种属相互作用

关联疾病

疾病名称

别名

Hypermobility Of Coccyx

Coccygeal Hypermobility Syndrome

Hypermobility Of The Coccyx

Klippel-Feil Syndrome 3

Superior Mesenteric Artery Syndrome

Wilkie Syndrome	Wilkie'S Syndrome
Arteriomesenteric Duodenal Compression Syndrome	Cast Syndrome
Vascular Compression Of The Duodenum	Smas
Arteriomesenteric Compression Of Duodenojejunal Flexure

Spinal Canal Intradural Extramedullary Neoplasm

Intradural Extramedullary Spinal Tumors

Intradural Extramedullary Spinal Canal Neoplasm

Kummell'S Disease

Traumatic Spondylopathy	Kummell Disease
Kummell'S Spondylitis	Kümmelll-Verneuil Disease
Kümmell Spondylitis	Kümmell Disease
Traumatic Spondylosis

Brown-Sequard Syndrome

Brown-Squard Syndrome	Hemicord Syndrome
Hemiparaplegic Syndrome	Hemispinal Cord Syndrome
Brown-Séquard Syndrome

Plexopathy

Discitis

Urocanase Deficiency

Encephalopathy Due To Urocanase Deficiency	Urocanate Hydratase Deficiency
Urocanic Aciduria	UROCD
High Urine Urocanic Acid Levels

Scheuermann Disease

Scheuermann'S Disease	Spinal Osteochondrosis
Juvenile Osteochondrosis Of Spine	Familial Scheuermann Disease
Familial Scheuermann Juvenile Kyphosis	Familial Spinal Osteochondrosis
Scheuermann Juvenile Kyphosis	Juvenile Osteochondritis Of The Spine
Juvenile Osteochondrosis Of Scheurermann	Scheuermann'S Kyphosis
Sherman'S Disease	Juvenile Kyphosis
Scheuermann Kyphosis	[X]Spinal Osteochondrosis, Unspecified

Tarsal Tunnel Syndrome

Neuropathy Of The Posterior Tibial Nerve And Its Branches	Posterior Tibial Nerve Neuralgia
Compression Of Posterior Tibial Nerve In Tarsal Tunnel

Epidural Abscess

Abscess Epidural

Tibial Neuropathy

Posterior Tibial Neuropathy

Spondylolysis

Acquired Spondylolysis

疾病名称	别名
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Cat. No.	产品名	作用方式	纯度	是否罕见病
HY-RS08302	MED31 Human Pre-designed siRNA Set A	Pre-designed Sets	/	否

直系同源

种属	基因名	来源	基因 ID
Felis catus	MED31	VGNC	VGNC:99276
Macaca mulatta	MED31	VGNC	VGNC:104630
Mus musculus	MED31	MGD	MGI:1914529
Bos taurus	MED31	VGNC	VGNC:31367
Canis familiaris	MED31	VGNC	VGNC:43138
Rattus norvegicus	MED31	RGD	RGD:1309457

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MedChemExpress (MCE) 只为有资质的科研机构、医药企业基于科学研究或药证申报的用途提供医药研发服务，不为任何个人或者非科研性质的、非用于药证申报使用等其他用途提供服务。

站点地图隐私声明

沪ICP备15051369号-4

上海工商

沪公网安备31011502019417

沪(浦)应急管危经许[2021]201709(QFYS)

营业执照（三证合一）

MED31 - mediator complex subunit 31 Gene

关于 MED31

功能概要

MED31 基因产物(1)

MED31 蛋白结构

MED31 蛋白互作信息

关联疾病

直系同源

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MED31 - mediator complex subunit 31 Gene

关于 MED31

功能概要

MED31 基因产物(1)

MED31 蛋白结构

MED31 蛋白互作信息

关联疾病

相关产品

直系同源

热门区域

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B

C

F

G

H

J

L

N

Q

S

T

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