1. Gene
  2. GOLGA7 - golgin A7 Gene

GOLGA7 - golgin A7 Gene

中文名称:高金 A7

种属: Homo sapiens

同用名: GCP16; GOLGA7A; HSPC041; GOLGA3AP1

基因 ID: 51125 | 基因类型: protein coding

关于 GOLGA7

Cytogenetic location: 8p11.21 Genomic coordinates (GRCh38): 8:41,490,396-41,510,980 (from NCBI)

This gene has 34 transcripts (splice variants), 289 orthologues and 1 paralogue. Ubiquitous expression in brain (RPKM 33.3), testis (RPKM 26.7) and 25 other tissues.

功能概要

参与高尔基体向质膜蛋白的转运;肽基-L-半胱氨酸 S-棕榈酰化;和蛋白质稳定。在高尔基体上游或内部作用于质膜运输。位于高尔基体膜和高尔基体堆栈。是高尔基体膜的固有成分。棕榈酰转移酶复合物的一部分。 [由基因组资源联盟提供,2022 年 4 月]

Involved in Golgi to plasma membrane protein transport; peptidyl-L-cysteine S-palmitoylation; and protein stabilization. Acts upstream of or within Golgi to plasma membrane transport. Located in Golgi membrane and Golgi stack. Is intrinsic component of Golgi membrane. Part of palmitoyltransferase complex. [provided by Alliance of Genome Resources, Apr 2022]

GOLGA7 基因产物(5)

mRNA Protein Name
NM_001002296.2 NP_001002296.1 golgin subfamily A member 7 isoform a
NM_001174124.2 NP_001167595.1 golgin subfamily A member 7 isoform b
NM_001362979.1 NP_001349908.1 golgin subfamily A member 7 isoform a
NM_001362980.2 NP_001349909.1 golgin subfamily A member 7 isoform a
NM_016099.3 NP_057183.2 golgin subfamily A member 7 isoform a
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
14522980 GOA
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in Golgi to plasma membrane protein transport IDA
IDA: 通过直接分析推断
14522980 GOA
acts upstream of or within Golgi to plasma membrane transport IDA
IDA: 通过直接分析推断
14522980 GOA
involved in peptidyl-L-cysteine S-palmitoylation IDA
IDA: 通过直接分析推断
16000296 GOA
involved in protein stabilization IDA
IDA: 通过直接分析推断
16000296 GOA
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in Golgi membrane IDA
IDA: 通过直接分析推断
14522980 GOA
located in Golgi stack IDA
IDA: 通过直接分析推断
14522980 GOA
part of palmitoyltransferase complex IDA
IDA: 通过直接分析推断
16000296 GOA
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断

GOLGA7 蛋白结构

Erf4

Erf4: Golgin subfamily A member 7/ERF4 family (12 - 122)

  • 0
  • 100
  • 137 a.a.
蛋白主名 其他名称

golgin subfamily A member 7

Golgi complex-associated protein of 16kDa

GOLGA7 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
Intra GOLGA7 Q7Z5G4 MID2 Homo sapiens Q9UJV3-2
Validated Y2H
32296183
Intra GOLGA7 Q7Z5G4 MID2 Homo sapiens Q9UJV3-2
Y2H Prey Pooling
32296183
Intra GOLGA7 Q7Z5G4 MID2 Homo sapiens Q9UJV3-2
Y2H Array
32296183
Intra GOLGA7 Q7Z5G4 KCNIP2 Homo sapiens Q9NS61-2
Validated Y2H
32296183
Cross GOLGA7 Q7Z5G4 S SARS-CoV-2 P0DTC2
Anti Tag CoIP
34117209
Cross GOLGA7 Q7Z5G4 S SARS-CoV-2 P0DTC2
Confocal
35115020
Intra GOLGA7 Q7Z5G4 FGFR3 Homo sapiens P22607
Y2H Pooling
32814053
Intra GOLGA7 Q7Z5G4 FGFR3 Homo sapiens P22607
Validated Y2H
32814053
Intra GOLGA7 Q7Z5G4 FGFR3 Homo sapiens P22607
Y2H Array
32814053
Intra GOLGA7 Q7Z5G4 MESD Homo sapiens Q14696
Y2H Array
32296183
Intra GOLGA7 Q7Z5G4 MESD Homo sapiens Q14696
Y2H Prey Pooling
32296183
Intra GOLGA7 Q7Z5G4 KCNIP3 Homo sapiens Q9Y2W7
Validated Y2H
32296183
种属间: 跨种属相互作用 种属内: 同种属相互作用

直系同源

种属 基因名 来源 基因 ID
Mus musculus GOLGA7 MGD MGI:1931029
Canis familiaris GOLGA7 VGNC VGNC:41342
Bos taurus GOLGA7 VGNC VGNC:29487
Rattus norvegicus GOLGA7 RGD RGD:1359725
Macaca mulatta GOLGA7 VGNC VGNC:73002